BMC Musculoskeletal Disorders

Table 4 Standardized regression weights (SRW) to quantify the role of psychosocial factors as mediators of the relation between physical activity and physical function following spine surgery

From: Role of psychosocial factors on the effect of physical activity on physical function in patients after lumbar spine surgery

	SRW					Overall
Mediators	M1	M2	M3	M4	M5	SRW	p-value	Mediation effect
Pain Self-Efficacy (PSE)
T1PA → T3 PF	0.28	0.27	0.28	0.30	0.31	0.29	0.0001	0%
T1 PA → T2 PSE	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.
T2 PSE → T3 PF	0.15	0.20	0.12	0.17	0.12	0.15	0.017
T2 PA → T4 PF	0.24	0.19	0.23	0.25	0.29	0.24	0.0001	0%
T2 PA → T3 PSE	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.
T3 PSE → T4 PF	0.11	0.12	0.14	0.22	0.03	0.13	0.13
Depression (Dep)
T1 PA → T3 PF	0.28	0.26	0.30	0.29	0.29	0.28	0.0001	3.43%
T1 PA → T2 Dep	-0.09	-0.08	-0.09	-0.07	-0.09	-0.08	0.108
T2 Dep → T3 PF	-0.12	-0.19	-0.12	-0.10	-0.09	-0.12	0.0266
T2 PA → T4 PF	0.24	0.18	0.24	0.21	0.24	0.22	0.0001	0%
T2 PA → T3 Dep	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.
T3 Dep → T4 PF	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.
Fear of Movement (Fear)
T1 PA → T3 PF	0.28	0.27	0.28	0.30	0.32	0.29	0.0001	5.38%
T1 PA → T2 Fear	-0.12	-0.14	-0.11	-0.13	-0.13	-0.12	0.0092
T2 Fear → T3 PF	-0.13	-0.12	-0.11	-0.15	-0.13	-0.13	0.0104
T2 PA → T4 PF	0.23	0.18	0.23	0.22	0.27	0.22	0.0001	0%
T2 PA → T3 Fear	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.
T3 Fear → T4 PF	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.

T1= 6 weeks, T2 = 6 months, T3 = 12 months, and T4 = 24 months following spine surgery
M1-M5 indicate the models for the five multiple imputation datasets
PA physical activity as measured by accelerometer (average steps per day), PF Physical function as measured by PROMIS scores, PSE Pain self-efficacy as measured by Pain Self-Efficacy Questionnaire, Dep Depressive symptoms measured using Patient Health Questionnaire-9, Fear Fear of movement as measured by 13-item Tampa Scale for Kinesiophobia, CFI Comparative Fit Index, TLI Tucker-Lewis Index, SRMR standardized root mean square residual, RMSEA root mean square error of approximation, n.s. not statistically significant

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