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Table 1 Demographics and BMD data of patients with SMA

From: Bone mineral density and its influencing factors in Chinese children with spinal muscular atrophy types 2 and 3

 

SMA 2 (n = 22)

SMA 3 (n = 18)

t/z/χ2

p-Value

Sex (male/female)

8/14

11/7

2.431

0.119

Age (y) at DXA

5.5 (4.1, 9.5)

5.4 (4.3, 3.9)

− 0.122

0.904

Disease course (y)

4.5 (3.2, 8.9)

3.9 (2.1, 5.4)

−1.251

0.219

TBLH BMD Z-scores

−3.7 ± 1.6

−2.0 ± 1.7

3.344

0.002

LS BMD Z-scores

−1.9 ± 1.2

−0.6 ± 1.4

3.266

0.002

ASMR Z-scores

−3.6 ± 1.1

−2.7 ± 1.3

2.476

0.018

Low BMD (%)

86.4

44.4

6.955

0.008

Osteoporosis(n)

0

1

  
  1. Data are shown as mean ± standard deviation or median (interquartile range). BMD bone mineral density, SMA spinal muscular atrophy, DXA dual-energy X-ray absorptiometry, TBLH total body less head, LS lumbar spine, ASMR appendicular skeletal muscle mass weight ratio