Fig. 1

Giant cell tumor originating in the Th12 vertebral body. a Axial computed tomography (CT), b reformatted sagittal plane, c sagittal plane T1-weighted image, d sagittal plane T2-weighted image, and e post-enhanced sagittal T1-weighted image showing lytic bony destruction in the Th12 vertebral body. (a) The lesion invaded the left pedicle and the margin was ill-defined. b–e The vertebral body had collapsed and the soft tissue of the anterior vertebral body had invaded the anterosuperior L1 vertebral body. e The lesion showed significant enhancement on contrast-enhanced magnetic resonance imaging (MRI). f Photomicrograph of the tissue from patient 1. Hematoxylin and eosin (H&E)-stained tissue section (200× magnification) demonstrated a highly cellular, solid neoplasm consisting of mononuclear cells as well as osteoclast-like giant cells