Variables | Responder n = 238 | Non-responder n = 51 | |||||
---|---|---|---|---|---|---|---|
Non-Fallers | Fallers | p-value1 | |||||
n | mean (± SD) | n | mean (± SD) |  | n | mean (± SD) | |
Demographics | |||||||
 Age (years) | 190 | 59.2 (± 11.9) | 48 | 63.7 (± 9.5) | 0.016 | 51 | 56.9 (± 9.4) |
  -Females | 147 | 58.4 (± 11.9) | 40 | 63.6 (± 9.9) | 0.013 | 43 | 56.7 (± 9.7) |
 Females, n, (%) | 190 | 147 (77.4) | 48 | 40 (83.3) | 0.368 | 51 | 43 (84.3) |
 Height (m) | 190 | 1.67 (± 0.08) | 48 | 1.64 (± 0.07) | 0.017 | 51 | 1.66 (± 0.08) |
 Weight (kg) | 190 | 77.3 (± 14.0) | 48 | 73.1 (± 12.0) | 0.059 | 51 | 75.3 (± 15.0) |
 BMI (kg/m2) | 190 | 27.1 (± 4.5) | 48 | 26.5 (± 4.0) | 0.401 | 51 | 26.9 (± 4.9) |
 Previous falls (yes), n, (%) | 190 | 25 (13.2) | 48 | 11 (22.9) | 0.092 | 51 | 14 (27.5) |
 Physical activity (yes), n, (%) | 190 | 137 (72.1) | 48 | 36 (75.0) | 0.688 | 51 | 26 (51.0) |
Medical data | |||||||
 RA disease duration (y)2 | 190 | 9.0 (4.0–16.0) | 48 | 11.0 (5.0–19.7) | 0.33 | 51 | 10.0 (6.0–19.0) |
 DAS28CRP (score)2 | 189 | 2.07 (1.62–2.85) | 45 | 2.33 (1.69–3.25) | 0.161 | 50 | 2.35 (1.64–3.03) |
  -Low disease activity ≤3.2, n, (%) |  | 154 (81.1) |  | 33 (66.8) | 0.229 |  | 39 (76.5) |
  -Moderate disease activity 3.2 ≤ 5.1, n, (%) |  | 34 (17.9) |  | 12 (25.0) |  | 9 (17.6) | |
  -High disease activity > 5.1, n, (%) |  | 1 (0.5) |  | 0 |  | 2 (3.9) | |
 HAQ (score)2 | 190 | 0.37 (0.0–1.12) | 48 | 0.81 (0.41–1.5) | 0.001 | 51 | 0.75 (0.0–1.5) |
Physical performance tests | |||||||
 Handgrip strength (kg) | 189 | 24.8 (± 9.0) | 48 | 22.45 (± 8.2) | 0.102 | 50 | 22.97 (± 8.1) |
 Gait speed (m/s) | 190 | 1.24 (± 0.21) | 48 | 1.23 (± 0.25) | 0.70 | 51 | 1.19 (± 0.2) |
 CRT (sec) | 187 | 9.43 (± 3.2) | 47 | 9.69 (±3.6) | 0.635 | 51 | 10.32 (± 3.8) |
 SPPB (total score)2 | 190 | 11.0 (11.0–12.0) | 48 | 11.0 (10.0–12.0) | 0.645 | 51 | 11.0 (10.0–12.0) |
 SPPB (score category) | |||||||
  -Poor performer: 0–6, n, (%) |  | 7 (3.7) |  | 1 (2.1) | 0.710 |  | 3 (5.9) |
  -Moderate performer: 7–9, n, (%) |  | 20 (10.5) |  | 7 (14.6) |  | 7 (13.7) | |
  -Good performer: 10–12, n, (%) |  | 163 (85.8) |  | 40 (83.3) |  | 41 (80.4) | |
 FICSIT-4 (score)2 | 190 | 5.0 (0.0) | 48 | 5.0 (4.0–5.0) | 0.030 | 51 | 5.0 (0.0) |
 Low FICSIT-4 (1–4), n, (%) | 190 | 28 (14.7) | 48 | 14 (29.2) | 0.019 | 51 | 10 (19.6) |
Lean mass DXA | |||||||
 ASM/h2 (kg/m2) | 190 | 6.89 (± 1.04) | 48 | 6.64 (± 0.9) | 0.13 | 51 | 6.73 (± 1.0) |
 ASM/BMI (m2) | 190 | 0.73 (± 0.1) | 48 | 0.69 (± 0.1) | 0.04 | 51 | 0.70 (± 0.1) |
Leonardo tests | |||||||
 CRTPrel (W/kg) | 182 | 10.35 (± 2.8) | 44 | 9.73 (± 2.5) | 0.18 | 49 | 9.45 (± 2.0) |
 2LJPrel (W/kg) | 169 | 27.19 (± 6.9) | 45 | 25.32 (± 5.3) | 0.05 | 45 | 25.60 (± 6.8) |
 EFI (%) | 169 | 81.20 (± 17.3) | 45 | 83.67 (± 16.0) | 0.38 | 45 | 75.74 (± 17.3) |