Fig. 1
From: Norepinephrine modulates IL-1β-induced catabolic response of human chondrocytes
The levels of beta-adrenergic receptors are decreased in OA cartilage. (A) The relative expression of β1-, β2-, and β3-adrenergic receptor (AR) in normal and OA cartilage. Data represent the mean ± standard deviation (SD) for duplicate data from different donors. Normal cartilage (n = 6); OA cartilage (n = 8). *P < 0.05 and ****P < 0.0001 vs. normal cartilage tissue by Mann-Whitney test. (B) Decreased expression of β1-, β2-, and β3-AR proteins in OA cartilage. The levels of β1-, β2-, and β3-AR protein were measured by immunohistochemistry (IHC) using antibodies against β1-, β2-, and β3- AR. Scale bars = 10 μm