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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: P2Y2 promotes fibroblasts activation and skeletal muscle fibrosis through AKT, ERK, and PKC

Fig. 1

P2Y2 exacerbated denervation caused skeletal muscle atrophy and fibrosis. a Representative pictures of masson staining of mouse gastrocnemius muscle different time after denervation. b Loss of muscle mass as a percentage of non-denervated control leg mass gastrocnemius at specified time (n = 5). c Fibrosis area of denervated gastrocnemius muscle was measured with Image J. WT, C57Bl/6 N wild type; KO, P2Y2 knockout. * p < 0.05 compared to wild type of the same time point

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