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Table 4 Summary of evidence of PTEs

From: Partial two-stage exchange: an alternative method for infected total hip arthroplasty

Reports Year Number of hips Organism profile Success rate Inclusion criteria
Reported By our criterion
Faroug et al 2009 2 P. aeruginosa and MRSA (1/2)
Culture-negative (1/2)
100% 100% Patients diagnosed with chronic PJI and partial components loosen;
Anagnostakos et al. 2010 12 S. epidermidis and S. aureus (most) 91.6% 91.6% Patients who had only late, deep septic acetabular cup loosening;
Lee et al. 2013 19 S. aureus and CNS (most)
Culture-negative (4/19)
N.A 89.5% Patients diagnosed with PJI and well-fixed cementless stems;
Ekpo et al. 2014 19 S. aureus and Streptococcus (most)
MRSA (3/19)
Culture-negative (4/19)
89.5% 89.5% Patients diagnosed with chronic PJI and well-fixed stems;
Lombardi et al. 2014 7 S. aureus and Streptococcus (5/7)
Culture-negative (2/7)
85.7% 85.7% (1) Patients diagnosed with possible PJI and well-fixed stems;
(2) Patients with a first-time infected THA in which removal of the femoral component would lead to compromise of proximal femoral bone stock;
(3) Elderly patients with significant co-morbidities who had a well-fixed femoral component and poor proximal bone stock;
(4) A well-fixed femoral component was directly adjacent to an ipsilateral well-fixed TKA femoral component;
Fukui et al. 2016 5 CNS (most) 80.0% 80.0% Patients diagnosed with PJI and well-fixed stems;
Zhou et al. 2019 26 CNS (9/26)
S. aureus (4/26)
MRSA (4/26)
Others (9/26)
100% 100% Patients diagnosed with PJI and partial components loosen;
Crawford et al. 2019 41 Staphylococcus (19/41)
MRSA (3/41)
Others (12/41)
Negative (7/41)
80.5% 80.5% (1) Patients diagnosed with chronic PJI and well-fixed stems;
(2) Removal of the femoral component would lead to significant femoral bone loss and compromise of future fixation;
Shi et al. 2020 14 Staphylococcus (12/14)
E. faecalis (1/14)
E. coli (1/14)
100% 92.9% (1) Patients diagnosed with chronic PJI and partial components loosen;
(2) Patients in worse health status with high risk of operation;
(3) Patients with a positive culture of pre-operative aspirated synovial fluid with sensitive antibiotics.
Current study N.A 28 Staphylococcus (18/28)
MRSA (2/28)
Others (2/28)
Negative (6/28)
N.A 85.7% (1) Patients diagnosed with chronic PJI and well-fixed stems;
(2) Removal of the femoral component would lead to significant femoral bone loss and compromise of future fixation;
(3) Elderly patients in worse health status with high risk of operation;
  1. MRSA methicillin-resistant staphylococcus aureus, PJI periprosthetic joint infection, CNS coagulase-negative Staphylococcus, N. A not available, THA total hip arthroplasty, TKA total knee arthroplasty