Table 3 Sensitivity, Specificity, PPV, NPV, and accuracy of inflammatory markers
Parameters | ESR (mm/h) | Serum CRP (mg/L) | Synovial PMN (%) | Synovial CRP (mg/L) | Serum CRP OR Synovial CRP (mg/L) | Serum CRP AND Synovial CRP (mg/L) |
|---|---|---|---|---|---|---|
AUC (95%CI) | 0.600 (0.495, 0.698) | 0.703 (0.601, 0.791) | 0.810 (0.718, 0.882) | 0.937 (0.869, 0.976) | / | / |
Cut-off level | 34 | 10.2 | 69.79 | 7.26 | Serum CRP > 10.2 OR Synovial CRP > 7.26 | Serum CRP > 10.2 AND Synovial CRP > 7.26 |
Sensitivity (%) (95%CI) | 51.28 (34.8, 67.6) | 84.62 (69.5, 94.1) | 84.62 (69.5, 94.1) | 84.62 (69.5, 94.1) | 97.44 (92.5, 100) | 71.79 (57.7, 85.9) |
Specificity (%) (95%CI) | 77.59 (64.7, 87.5) | 56.90 (43.2, 69.8) | 74.14 (61.0, 84.7) | 93.10 (83.3, 98.1) | 50.00 (37.1, 62.9) | 100 (/) |
PPV (%) | 60.6 (46.6, 73.1) | 56.9 (48.8, 64.6) | 68.7 (58.2,77.6) | 89.2 (76.0, 95.5) | 56.72 (44.9, 68.6) | 100 (/) |
NPV (%) | 70.3 (62.5, 77.1) | 84.6 (71.8, 92.2) | 87.8 (77.2, 93.8) | 90.0 (81.1, 95.0) | 96.67 (90.2, 100) | 84.06 (75.4, 92.7) |
Accuracy (%) | 67.01 | 68.04 | 78.35 | 89.69 | 69.07 | 88.66 |