First author, publication year (reference no) | Study design | Number of participants | Intervention duration | Type of the knee valgus brace | Used-questionnaire | The direction of effect, as indicated in the manuscript |
---|---|---|---|---|---|---|
Jones et al.,2013 [6] | crossover randomized | 28 (12f, 16 m) | 2 weeks | Donjoy-OA Adjuster, DJO, Vista, USA) | WOMAC VAS pain | ↑ |
Haladik et al. 2014 [1] | prospective cohort | 10 (1f, 9 m) | 2 weeks | OA Adjuster | WOMAC | ↑ |
Fu et al., 2015 [21] | non-randomized prospective cohort | 10 (4f, 6 m) | 4 weeks | Unloader valgus knee braces (Ossurhf, Reykjavik, Iceland) | WOMAC VAS pain | ↑ |
Polloet al., 2002 [22] | prospective cohort | 11 (1f, 10 m) | 2 weeks | Generation II Un-loader ADJ brace, Generation II US | VAS pain | ↑ |
Schmalz et al., 2010 [23] | prospective cohort | 16 (8f, 8 m) | 4 weeks | Genu Arthro knee brace | VAS pain | ↑ |
Ramsey et al., 2007 [7] | prospective cohort | 16 (not available) | 2 weeks | GenerationII Unloader Select, Generation II USA, Inc., Bothell, Washington | KOOS | – |
Hsieh et al.,2020 [24] | comparative study | 20 (13f, 7 m) | 1 month and 3 months | Thruster Legacy OA brace | WOMAC VAS pain | ↑ |
Briggs et al. 2012 [25] | prospective cohort | 39 (16f,23 m) | 3 week, 6 weeks, and 6 months | unloader brace | WOMAC SF36 | ↑ |
van Egmondet al., 2017 [26] | randomized controlled trial | 100.In Bledsoe Thrustergroup 50 (20f, 30 m).InSofTec group 50 (22f, 28 m) | 2 weeks and 12 weeks | the Bledsoe Thrusterbrace (B&Co Inc. N.V., Sint-Antelinks, Belgium) andtheSofTec OA Brace (Bauerfeind AG, Zeulenroda-Triebes, Germany) | VAS pain WOMAC SF-36 | ↑ |
Barne et al., 2002 [27] | prospective cohort | 30 (12f, 18 m) | 8 weeks | Counterforce brace (breg, calif) | SF-36 | ↑ |
Thoumie et al., 2018 [28] | randomized controlled trial | 32 (24f, 8 m) | 6 weeks | The REBELRELIEVER unloading knee brace | VAS pain (100 mm) | ↑ |
Gaasbeek et al.,2007 [16] | prospective cohort | 15 (3f, 12 m) | 6 weeks | The SofTec OA valgus brace | WOMAC VAS pain | ↑ |
Laroche et al., 2014 [29] | prospective cohort | 20 (16f, 5 m) | 5 weeks | PROTEOR (France)/ ODRA® brace | WOMAC | ↑ |
Draganich et al.,2006 [18] | Crossover | 10 (not available) | 5 weeks | Adjustable OA Defiance; dj Orthopedics) | WOMAC | ↑ |
Ornetti et al., 2015 [30] | prospective cohort | 20 (16f, 4 m) | 6 weeks and 52 weeks | OdrA brace | KOOS VAS pain | ↑ |
Arazpour et al., 2013 [31] | randomized prospective cohort | 12 (8f, 4 m) | 6 weeks | Custom-made knee valgus brace | VAS pain | ↑ |
RobertLachaine et al., 2020 [17] | randomized crossover | 24 (10f, 14 m) | 3 months | valgus three-point bending system brace (V3Pbrace), an unloader brace with valgus and external rotation functions (VERbrace) and a stabilizing brace | WOMAC KOOS | ↑ |
Hurley et al., 2012 [32] | prospective cohort | 24 (4f, 20 m) | 6 months | Breg Fusion valgus unloader braces (custom-made) | WOMAC SF36 | – |
Iqbal, 2014 [33] | randomized controlled trial | 60 (24f, 36 m) | 6 months | Custom-made off-loading knee braces | VAS pain (mm) VAS activity (%) | ↑ |
Richards et al., 2005 [34] | crossover study | 12 (5f, 7 m) | 6 months | GII Orthotics-Europe, Eindhoven, The Netherlands | VAS pain | ↑ |
van Raaij, et al. 2010 [35] | randomized controlled trial | 46 (35f, 11 m) | 6 months | the MOS Genu1 knee brace | WOMAC Function VAS pain | ↑ |
Ostrander et al., 2016 [36] | randomized controlled trial | 16 (8f,8 m) | 24 weeks | a medial-unloader brace (Fusion OA; Breg, Inc) | KOOS VAS pain | ↑ |
Hjartarson and Toksvig-Larsen, 2018 [12] | randomized controlled trial | 52 out 74 finished one year study | One year | Unloader One® Knee Brace (Ossur,Iceland) | KOOS | – |
Sattari&Ashraf,2011 [37] | randomized controlled trial | 20 (63%f, 37%m) | 9 months | The generation II of knee orthosis | VAS pain | ↑ |