Table 2 Characteristics in each cohort
AMS-OA (5) | STABILO (17) | NEXA (18) | CBT (19) | VIDEX (20) | Total sample | |
|---|---|---|---|---|---|---|
N | 553 | 159 | 100 | 222 | 177 | 1211 |
N with exercise therapy | 0 | 159 | 100 | 148 | 177 | 584 |
Demographics | ||||||
Gender (female), n (%) | 397 (72%) | 97 (61%) | 52 (52%) | 133 (60%) | 107 (61%) | 786 (65%) |
Age (years), mean ± SD | 62.9 ± 9.4 | 61.9 ± 7.1 | 62.4 ± 7.3 | 63.4 ± 8.0 | 67.6 ± 5.8 | 63.5 ± 8.4 |
Radiographic severity: | ||||||
K&L grade 0/1, n (%) | 185 (38%) | 49 (31%) | 0 (0%) | 0 (0%) | 61 (35%) | 296 (26%) |
K&L grade 2, n (%) | 125 (25%) | 44 (28%) | 22 (22%) | 90 (41%) | 59 (33%) | 340 (30%) |
K&L grade 3, n (%) | 97 (20%) | 45 (28%) | 43 (43%) | 63 (28%) | 29 (16%) | 277 (24%) |
K&L grade 4, n (%) | 86 (17%) | 21 (13%) | 35 (35%) | 69 (31%) | 28 (16%) | 239 (21%) |
History of knee surgery, n (%) | n/a | n/a | 49 (49%) | 91 (41%) | n/a | 140 (44%) |
Nr. of comorbidities (CIRS ≥2): | ||||||
0, n (%) | 259 (48%) | n/a | n/a | n/a | 131 (76%) | 390 (55%) |
1, n (%) | 152 (28%) | 42 (24%) | 194 (27%) | |||
2, n [5] | 73 (14%) | 0 (0%) | 73 (10%) | |||
≥ 3, n (%) | 58 (11%) | 0 (0%) | 58 (8%) | |||
AMS-OA (5) | STABILO (14) | NEXA (15) | CBT (16) | VIDEX (17) | Total sample | |
Outcome variables | ||||||
Knee pain (0–10, NRS/VAS), mean ± SD | 5.8 ± 2.4 | 5.0 ± 2.1 | 5.4 ± 1.5 | 5.9 ± 1.3 | 4.7 ± 2.2 | 5.5 ± 2.1 |
Physical function (0–100, WOMAC), mean ± SD | 47.1 ± 20.5 | 38.5 ± 18.0 | 40.0 ± 14.1 | 51.4 ± 10.7 | 30.7 ± 19.3 | 43.7 ± 19.2 |
Stratification variables | ||||||
Body mass index (kg/m2), mean ± SD | 31.9 ± 6.7 | 29.0 ± 4.6 | 29.6 ± 4.1 | 31.1 ± 6.1 | 28.2 ± 4.4 | 30.6 ± 6.0 |
Quadriceps strength (Nm/kg), mean ± SD | 0.84 ± 0.53 | 0.98 ± 0.51 | n/a | n/a | 1.12 ± 0.49 | 0.92 ± 0.53 |
30s-CST (repetitions), mean ± SD | n/a | n/a | 10.7 ± 2.6 | 8.7 ± 2.7 | n/a | 9.3 ± 2.8 |