Skip to main content

Table 2 Characteristics in each cohort

From: Construct validity of the OCTOPuS stratification algorithm for allocating patients with knee osteoarthritis into subgroups

  AMS-OA (5) STABILO (17) NEXA (18) CBT (19) VIDEX (20) Total sample
N 553 159 100 222 177 1211
N with exercise therapy 0 159 100 148 177 584
Demographics
 Gender (female), n (%) 397 (72%) 97 (61%) 52 (52%) 133 (60%) 107 (61%) 786 (65%)
 Age (years), mean ± SD 62.9 ± 9.4 61.9 ± 7.1 62.4 ± 7.3 63.4 ± 8.0 67.6 ± 5.8 63.5 ± 8.4
 Radiographic severity:
  K&L grade 0/1, n (%) 185 (38%) 49 (31%) 0 (0%) 0 (0%) 61 (35%) 296 (26%)
  K&L grade 2, n (%) 125 (25%) 44 (28%) 22 (22%) 90 (41%) 59 (33%) 340 (30%)
  K&L grade 3, n (%) 97 (20%) 45 (28%) 43 (43%) 63 (28%) 29 (16%) 277 (24%)
  K&L grade 4, n (%) 86 (17%) 21 (13%) 35 (35%) 69 (31%) 28 (16%) 239 (21%)
 History of knee surgery, n (%) n/a n/a 49 (49%) 91 (41%) n/a 140 (44%)
 Nr. of comorbidities (CIRS ≥2):
  0, n (%) 259 (48%) n/a n/a n/a 131 (76%) 390 (55%)
  1, n (%) 152 (28%) 42 (24%) 194 (27%)
  2, n [5] 73 (14%) 0 (0%) 73 (10%)
   ≥ 3, n (%) 58 (11%) 0 (0%) 58 (8%)
  AMS-OA (5) STABILO (14) NEXA (15) CBT (16) VIDEX (17) Total sample
Outcome variables
 Knee pain (0–10, NRS/VAS), mean ± SD 5.8 ± 2.4 5.0 ± 2.1 5.4 ± 1.5 5.9 ± 1.3 4.7 ± 2.2 5.5 ± 2.1
 Physical function (0–100, WOMAC), mean ± SD 47.1 ± 20.5 38.5 ± 18.0 40.0 ± 14.1 51.4 ± 10.7 30.7 ± 19.3 43.7 ± 19.2
Stratification variables
 Body mass index (kg/m2), mean ± SD 31.9 ± 6.7 29.0 ± 4.6 29.6 ± 4.1 31.1 ± 6.1 28.2 ± 4.4 30.6 ± 6.0
 Quadriceps strength (Nm/kg), mean ± SD 0.84 ± 0.53 0.98 ± 0.51 n/a n/a 1.12 ± 0.49 0.92 ± 0.53
 30s-CST (repetitions), mean ± SD n/a n/a 10.7 ± 2.6 8.7 ± 2.7 n/a 9.3 ± 2.8
  1. K/L = Kellgren & Lawrence; CIRS = Cumulative Illness Rating Score; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index; NRS = Numeric Rating Scale; VAS = Visual Analogue Scale; 30s-CST = 30 s chair stand test; n/a = not applicable (not assessed)