|
N
|
553
|
159
|
100
|
222
|
177
|
1211
|
|
N with exercise therapy
|
0
|
159
|
100
|
148
|
177
|
584
|
|
Demographics
|
|
Gender (female), n (%)
|
397 (72%)
|
97 (61%)
|
52 (52%)
|
133 (60%)
|
107 (61%)
|
786 (65%)
|
|
Age (years), mean ± SD
|
62.9 ± 9.4
|
61.9 ± 7.1
|
62.4 ± 7.3
|
63.4 ± 8.0
|
67.6 ± 5.8
|
63.5 ± 8.4
|
|
Radiographic severity:
|
|
K&L grade 0/1, n (%)
|
185 (38%)
|
49 (31%)
|
0 (0%)
|
0 (0%)
|
61 (35%)
|
296 (26%)
|
|
K&L grade 2, n (%)
|
125 (25%)
|
44 (28%)
|
22 (22%)
|
90 (41%)
|
59 (33%)
|
340 (30%)
|
|
K&L grade 3, n (%)
|
97 (20%)
|
45 (28%)
|
43 (43%)
|
63 (28%)
|
29 (16%)
|
277 (24%)
|
|
K&L grade 4, n (%)
|
86 (17%)
|
21 (13%)
|
35 (35%)
|
69 (31%)
|
28 (16%)
|
239 (21%)
|
|
History of knee surgery, n (%)
|
n/a
|
n/a
|
49 (49%)
|
91 (41%)
|
n/a
|
140 (44%)
|
|
Nr. of comorbidities (CIRS ≥2):
|
|
0, n (%)
|
259 (48%)
|
n/a
|
n/a
|
n/a
|
131 (76%)
|
390 (55%)
|
|
1, n (%)
|
152 (28%)
|
42 (24%)
|
194 (27%)
|
|
2, n [5]
|
73 (14%)
|
0 (0%)
|
73 (10%)
|
|
≥ 3, n (%)
|
58 (11%)
|
0 (0%)
|
58 (8%)
|
| |
AMS-OA (5)
|
STABILO (14)
|
NEXA (15)
|
CBT (16)
|
VIDEX (17)
|
Total sample
|
|
Outcome variables
|
|
Knee pain (0–10, NRS/VAS), mean ± SD
|
5.8 ± 2.4
|
5.0 ± 2.1
|
5.4 ± 1.5
|
5.9 ± 1.3
|
4.7 ± 2.2
|
5.5 ± 2.1
|
|
Physical function (0–100, WOMAC), mean ± SD
|
47.1 ± 20.5
|
38.5 ± 18.0
|
40.0 ± 14.1
|
51.4 ± 10.7
|
30.7 ± 19.3
|
43.7 ± 19.2
|
|
Stratification variables
|
|
Body mass index (kg/m2), mean ± SD
|
31.9 ± 6.7
|
29.0 ± 4.6
|
29.6 ± 4.1
|
31.1 ± 6.1
|
28.2 ± 4.4
|
30.6 ± 6.0
|
|
Quadriceps strength (Nm/kg), mean ± SD
|
0.84 ± 0.53
|
0.98 ± 0.51
|
n/a
|
n/a
|
1.12 ± 0.49
|
0.92 ± 0.53
|
|
30s-CST (repetitions), mean ± SD
|
n/a
|
n/a
|
10.7 ± 2.6
|
8.7 ± 2.7
|
n/a
|
9.3 ± 2.8
|
