From: Cross-cultural adaptation and validation of the German Central Sensitization Inventory (CSI-GE)
Hypothesis- Group Comparison | Expected Outcome | Results | Was the Hypothesis met? |
CSI score of the HC group | HC group scoring the lowest | HC group showed lowest mean CSI-GE score, significantly different from all but the RCP group | Yes |
CSI score of the FMS group | FMS group scoring the highest of all pain groups | highest mean CSI-GE score, significantly different from all but the MCP group | Yes |
CSI score of the MCP group | MCP group scoring high in comparison to other pain groups but probably lower than the FMS group | Second highest mean CSI-GE score of all 5 pain groups | Yes |
CSI score of the RCP group | RCP group scoring low in comparison to other pain groups | Lowest mean CSI-GE score of all 5 pain groups but higher than HC group (although not significant) | Yes |
CSI Score of the RAR group | RAR group Scoring lower in comparison to FMS and MCP | Lower mean CSI–GE score than in FMS and in MCP groups | Yes |
Questionnaire- Correlations with CSI-GE Score | Expected Outcome | Kendal’s τ, the associated Holm adjusted p value and classification | Was the Hypothesis met? |
CS is related to subjective pain sensitivity | High correlation between CSI-GE and PSQminor | τ = 0.23; p < 0.001; low | No |
CS is related to somatization or general symptom load | At least medium correlation between CSI-GE and (a) PHQ15 and (b) FSQ subscale SSS | a: τ = 0.57; p < 0.001; medium b: τ = 0.56; p < 0.001; medium | Yes |
CS is related to spread of pain | At least medium correlation between CSI-GE and FSQ subscale WPI | τ = 0.47; p < 0.001; low | No |
CS is related to neuropathic pain characteristics | At least medium correlation between CSI-GE and PainDETECT | τ = 0.43; p < 0.001; low | No |
CS is related to chronification of pain | At least medium correlation between CSI-GE and MPSS | τ = 0.32; p < 0.001; low | No |
CS is related to pain catastrophizing | At least medium correlation between CSI-GE and PCS | τ = 0.28; p < 0.001; low | No |
How many Hypotheses were met? | 6/11 (55%) |