|
Demographic
|
|
Age, years, mean (SD)
|
60.4 (10c.4)
|
59.4 (10.3)
|
0.275
|
|
Disease duration, years, median [IQR]
|
NA
|
5.5[1.5;13.0]
|
NA
|
|
BMI, Kg/m2, mean (SD)
|
22.8 (3.6)
|
22.1 (3.4)
|
0.031
|
|
Female, n (%)
|
146 (73.7)
|
317 (78.3)
|
0.256
|
|
Menopause status of female, n (%)
| | |
< 0.001*
|
|
Post-menopause, age > 45
|
104 (71.2)
|
186 (58.7)
| |
|
Early menopause, age ≤ 45
|
25 (17.1)
|
38 (12.0)
| |
|
Lifestyle
|
|
Smoking, ever or current, yes, n (%)
|
17 (8.6)
|
36 (8.9)
|
0.937
|
|
Drinking, ever or current, yes, n (%)
|
18 (9.1)
|
18 (4.4)
|
0.035
|
|
Medical history
|
|
Diabetes mellitus
|
35 (17.7)
|
47 (11.6)
|
0.055
|
|
Hypertension
|
75 (37.9)
|
77 (19.0)
|
< 0.001
|
|
Coronary heart disease
|
20 (10.1)
|
20 (4.9)
|
0.027
|
|
Hyperuricemia
|
15 (7.6)
|
43 (10.6)
|
0.297
|
|
Dyslipidemia
|
58 (29.3)
|
56 (13.8)
|
< 0.001
|
|
Femoral neck necrosis
|
1 (0.5)
|
8 (2.0)
|
0.268
|
|
Osteoporotic fracture
|
0
|
20 (4.9)
|
NA
|
|
Anti-osteoporotic medication
|
6 (3.0)
|
29 (7.2)
|
0.641
|
|
Laboratory
|
|
Serum calcium level, mmol /L, mean (SD)
|
2.4 (0.2)
|
2.3 (0.1)
|
< 0.001
|
|
Serum phosphate level, mmol /L, mean (SD)
|
1.9 (8.1)
|
1.2 (0.4)
|
0.272
|
|
Serum creatinine level, μmol /L, mean (SD)
|
67.2 (32.9)
|
62.6 (20.5)
|
0.086
|
|
Serum Uric acid level, μmol /L, mean (SD)
|
327.9 (101.2)
|
314.1 (103.9)
|
0.146
|
|
Serum 25(OH)D3 level, nmol /L, mean (SD)
|
65.6 (22.1)
|
76.7 (32.9)
|
0.006
|
|
Vitamin D insufficiency, yes, n (%)
|
65 (32.8)
|
145 (35.8)
|
0.046*
|
|
Hypovitaminosis D, yes, n (%)
|
43 (21.7)
|
118 (29.1)
|
0.046*
|
