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Fig. 7 | BMC Musculoskeletal Disorders

Fig. 7

From: In vitro and in vivo tenocyte-protective effectiveness of dehydroepiandrosterone against high glucose-induced oxidative stress

Fig. 7

Quantitative real-time PCR analysis (in vivo). Relative fold changes in messenger RNA (mRNA) levels in the tendon. The mRNA expressions of NADPH oxidase (NOX)1, interleukin (IL)-6, matrix metalloproteinase (MMP)-2, tissue inhibitors of matrix metalloproteinase (TIMP)-2, and type III collagen (col3) in diabetic rat Achilles tendons were significantly lower in the dehydroepiandrosterone (DHEA) group than in the control group. (*p < 0.05). No significant difference between control and diabetic rats was seen in the expression of NOX4. The expression of type I collagen (col1) was significantly higher in the DHEA group than in the control group

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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