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Fig. 6 | BMC Musculoskeletal Disorders

Fig. 6

From: In vitro and in vivo tenocyte-protective effectiveness of dehydroepiandrosterone against high glucose-induced oxidative stress

Fig. 6

Immunohistochemical staining for NOX1 and NOX4 expression. (A) Immunohistochemical staining for NADPH oxidase (NOX)1 and NOX4 expression (brown) in the diabetic rat Achilles tendon. Increased expression of NOX1 in Achilles tendon was observed in dehydroepiandrosterone (DHEA) group compared with control group. There was no difference in the expression of NOX4 between DHEA and control group. (B) Semi-quantitative analysis of cells positive for NADPH oxidase (NOX)1 (left) and NOX4 (right). The ratio of NOX1-positive cells in diabetic rat Achilles tendon was significantly higher in dehydroepiandrosterone (DHEA) group than in control group. (*p < 0.05). No significant difference was observed between control and DHEA group in the ratio of NOX4-positive cells

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