Skip to main content

Table 3 Comparison of patient characteristics between the PD responders and non-PD responders

From: Association between serum bone biomarker levels and therapeutic response to abatacept in patients with rheumatoid arthritis (RA): a multicenter, prospective, and observational RA ultrasound cohort study in Japan

  PD responders
n = 30
Non-PD responders
n = 29
p-value
Age, yrs 74 (67–78) 70 (62–74) 0.058
Male, n 8 (26.7) 8 (27.6) 1.00
Disease duration, months 92 (26–258) 39 (10–156) 0.071
Positive RF, n 27 (90.0) 19 (65.5) 0.030
Positive ACPA, n 28 (93.3) 24 (82.8) 0.21
SDAI 25.0 (16.6–36.5) 18.2 (12.2–24.5) 0.0081
Total GS score 19 (13–28) 8 (4–15) 0.0005
Total PD score 11 (7–20) 4 (1–7) < 0.0001
Dkk-1, pg/ml 3040 (2489–3652) 3699 (2676–4477) 0.026
SOST, pg/ml 2428 (1721–3057) 2803 (2137–3916) 0.058
OC, pg/ml 16,588 (9582–28,327) 17,722 (12512–39,103) 0.54
OPG, pg/ml 958 (749–1190) 945 (839–1534) 0.32
OPN, pg/ml 23,035 (17382–40,435) 22,928 (17305–35,962) 0.93
  1. ACPA Anti-cyclic citrullinated peptide antibody, OC Osteocalcin, OPG Osteoprotegrin, OPN Osteopontin, PD Power Doppler, RF Rheumatoid factor, SDAI Simplified Disease Activity Index, SOST Sclerostin