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Table 3 Secondary outcomes regarding VAS scores for resting pain

From: Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study

Time after surgery

Duloxetine* (n = 48)

Placebo* (n = 48)

P value†

3 h

4.1 ± 1.0

4.5 ± 1.1

0.026

6 h

4.0 ± 1.0

4.4 ± 1.0

0.032

12 h

3.3 ± 1.0

3.8 ± 1.1

0.044

24 h

3.0 ± 1.1

3.5 ± 1.1

0.046

48 h

2.3 ± 1.0

2.8 ± 1.0

0.019

72 h

1.8 ± 0.9

2.2 ± 1.0

0.023

1w

1.0 ± 0.8

1.3 ± 0.8

0.040

3w

0.8 ± 0.7

1.1 ± 0.7

0.043

3 m

0.6 ± 0.5

0.7 ± 0.6

0.851

  1. *The values are given as the mean and standard deviation. †P values are calculated by independent t-test. P values indicating a significant difference among groups are in bold