Table 5 Diagnostic value of biomarkers for acute and chronic PJI treated with DAIR
From: The role of fibrinogen in predicting reinfection after DAIR for periprosthetic joint infections
Values of biomarkers | Acute PJI (n = 23), Reinfection (n = 11) | Chronic PJI (n = 21), Reinfection (n = 15) |
|---|---|---|
ESR | ||
 AUC | 0.63 | 0.56 |
 Optimal cutoff | 22 mm/h | 20 mm/h |
 Youden index | 0.33 | 0.23 |
 Sensitivity | 90.91% | 66.00% |
 Specificity | 41.67% | 16.66% |
 PPV | 58.80% | 66.66% |
 NPV | 83.30% | 16.66% |
CRP | ||
 AUC | 0.56 | 0.58 |
 Optimal cutoff | 58.62 mg/L | 16.50 mg/L |
 Youden index | 0.23 | 0.37 |
 Sensitivity | 72.73% | 53.33% |
 Specificity | 50.00% | 66.66% |
 PPV | 57.10% | 80.00% |
 NPV | 66.70% | 36.36% |
FIB | ||
 AUC | 0.75 | 0.81 |
 Optimal cutoff | 3.32 g/L | 3.94 g/L |
 Youden index | 0.65 | 0.63 |
 Sensitivity | 81.82% | 80.00% |
 Specificity | 83.33% | 66.66% |
 PPV | 81.80% | 85.71% |
 NPV | 83.30% | 57.14% |