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Table 5 Change of treatment status at time of follow-up in relation to EQ-5D

From: Responsiveness of the EuroQoL 5-Dimension (EQ-5D) questionnaire in patients with spondyloarthritis

At follow-up   % (n) EQ-5D scores Change of EQ-5D scores p-valuea EQ-VAS Change of EQ-VAS p-valuea
Baseline Follow-up Baseline Follow-up
Change of treatment Yes 13.2% (20) 0.76 (0.21) 0.75 (0.26) -0.03 (0.13) 0.742 64.75 (19.27) 65.25 (21.18) 0.50 (17.06) 0.870
No 86.8% (131) 0.80 (0.18) 0.80 (0.17) 0.00 (0.11) 63.74 (17.85) 65.12 (17.70) 1.42 (21.10)
Change of biologics Yes 2.6% (4) 0.71 (0.29) 0.81 (0.06) -0.05 (0.11) 0.459 58.00 (32.29) 63.75 (24.96) 5.75 (14.57) 0.644
No 97.4% (147) 0.80 (0.18) 0.79 (0.19) 0.00 (0.11) 64.03 (17.60) 65.18 (18.01) 1.18 (20.72)
Change of NSAIDs/COX-2 Inhibitors Yes 1.3% (2) 0.71 (0.24) 0.75 (0.28) 0.04 (0.04) 0.236 52.50 (24.75) 55.00 (21.21) 2.50 (3.54) 0.889
No 98.7% (149) 0.80 (0.18) 0.79 (0.18) 0.00 (0.11) 64.03 (17.94) 65.28 (18.12) 1.28 (20.70)
Change of DMARDs Yes 2.0% (3) 0.81 (0.10) 0.87 (0.05) 0.10 (0.14) 0.262 66.67 (15.28) 66.67 (20.82) 0.00 (10.00) 0.835
No 98.0% (148) 0.80 (0.18) 0.79 (0.19) -0.01 (0.11) 63.82 (18.07) 65.11 (18.14) 1.33 (20.73)
Addition of NSAIDs/COX-2 Inhibitors Yes 2.0% (3) 0.72 (0.38) 0.59 (0.61) -0.13 (0.23) 0.340 65.67 (13.65) 86.67 (7.64) 21.00 (8.54) 0.039*
No 98.0% (148) 0.80 (0.18) 0.80 (0.16) 0.00 (0.11) 63.84 (18.09) 64.70 (18.01) 0.90 (20.55)
Addition of DMARDs Yes 2.0% (3) 0.90 (0.06) 0.91 (0.04) 0.03 (0.04) 0.579 78.33 (7.64) 56.67 (32.15) -21.67 (25.66) 0.081
No 98.0% (148) 0.79 (0.18) 0.79 (0.18) 0.00 (0.11) 63.58 (18.02) 65.31 (17.87) 1.77 (20.28)
Addition of biologics Yes 4.0% (6) 0.76 (0.14) 0.72 (0.11) -0.05 (0.06) 0.123 66.00 (16.31) 65.83 (18.55) -0.17 (10.68) 0.672
No 96.0% (145) 0.80 (0.18) 0.80 (0.19) 0.00 (0.12) 63.78 (18.10) 65.11 (18.17) 1.36 (20.89)
  1. NSAIDs non-steroidal anti-inflammatory drugs, COX-2 Cyclooxygenase-2; DMARDs Disease-modifying anti-rheumatic drugs (including sulphasalazine, methotrexate, leflunomide); EQ-5D EuroQol 5-dimension; EQ-VAS EuroQol visual analogue scale
  2. a Mann-Whitney U test for comparison of change of scores/VAS between Yes and No groups *denotes statistical significance p<0.05