Outcome | Pooled mean difference (MD) | |||||
---|---|---|---|---|---|---|
No. Studies | WOMAC (/96) | P | No. Studies | VAS (/10) | P | |
3 months | 3 | −2.15 [−5.65, 1.35] | 0.23 | 4 | − 0.51 [− 1.02, 0.01] | 0.05 |
6 months | 4 | −9.51 [− 15.20, −3.83] | 0.05 | 4 | − 0.97 [− 1.94, 0.00] | 0.05 |
6 months: KL 1–2 | 1 | −3.86 [−6.01, − 1.71] | 0.0004 | 1 | −0.28 [− 0.97, 0.41] | 0.43 |
6 months: KL 2–3 | 2 | − 9.10 [− 15.73, − 2.46] | 0.007 | 2 | − 0.68 [− 2.01, 0.65] | 0.32 |
9 months* | 1 | −8.04 [− 10.19, − 5.89] | < 0.00001 | – | – | – |
12 months | 2 | − 8.10 [− 23.86, 7.65] | 0.31 | 2 | −0.07 [− 0.42, 0.28] | 0.69 |
LP-PRP | 2 | − 7.95 [− 18.14, 2.24] | 0.13 | 2 | −0.39 [− 1.01, 0.23] | 0.22 |
LR-PRP | 2 | − 11.26 [− 19.88, − 2.64] | 0.01 | 5 | − 0.98 [− 1.80, − 0.16] | 0.02 |
Triple PRP injection | 2 | −9.65 [− 21.35, 2.04] | 0.11 | 3 | −1.30 [− 2.33, − 0.26] | 0.01 |
Single PRP Injection | 2 | −9.10 [− 15.75, − 2.46] | 0.007 | 44 | − 0.26 [− 1.03, 0.52] | 0.52 |