Intra-articular platelet-rich plasma injections versus intra-articular corticosteroid injections for symptomatic management of knee osteoarthritis: systematic review and meta-analysis

Table 2 Results from each Performed Analysis (SMD)

Pain Score Reduction (WOMAC/VAS)
Outcome	Number of studies	Pooled SMD (95 CI)	P	Heterogeneity
Outcome	Number of studies	Pooled SMD (95 CI)	P	I² (%)	P
1 month	4	−0.07 [−0.49, 0.35]	0.74	65	0.03
3 month	6	−0.51 [− 0.90, − 0.12]	0.01	72	0.003
6 month	7	−0.78 [− 1.34, − 0.23]	0.005	88	< 0.00001
9 months	1	− 1.63 [− 2.14, − 1.12]	< 0.00001	n/a	n/a
12 months	2	−1.12 [− 3.34, 1.09]	0.32	97	< 0.00001
LP-PRP	3	−0.61 [− 0.92, − 0.29]	0.00002	16	0.31
LR-PRP	5	−0.98 [−1.79, − 0.17]	0.02	92	< 0.00001
Single PRP injection	5	−0.52 [−1.11, 0.07]	0.08	87	< 0.00001
Triple PRP Injection	2^a	−0.94 [−1.31, − 0.58]	< 0.00001	12	0.29

^aUslu et al. [20] excluded from the analysis for significant statistical heterogeneity

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