From: Prolonged antibiotic prophylaxis use in elective orthopaedic surgery – a cross-sectional analysis
Characteristics | SAP (N = 1137) | PSAP (N = 155) | P-Value |
---|---|---|---|
Antibiotic agent | 0.003 | ||
Cefuroxime | 1000 (88%) | 147 (95%) | |
Vancomycin | 4 (0.35%) | 3 (1.9%) | |
Clavulanic acid/ amoxicillin | 0 (0.00%) | 1 (0.65%) | |
Clindamycin | 8 (0.70%) | 4 (2.6%) | |
Number of consecutive post-operative intake doses < 24 h (number of patients) | |||
0 | 125 (11%) | 0 | |
1 | 12 (1.1%) | 0 | |
2 | 999 (87.8%) | 155 (100%)a | |
3 | 1 (0.1%) | 0 | |
Route of administration < 24 h | 1.00 | ||
IV (intravenous) | 1006 (88%) | 154 (99%) | |
p.o. (peroral) | 6 (0.53%) | 1 (0.65%) | |
Number of consecutive intake doses ≥24 h (number of doses) | n/a | 3.3 (1.5) | |
Route of administration ≥24 h | |||
IV (intravenous) | n/a | 152 (98%) | |
p.o. (peroral) | n/a | 3 (1.9%) | |
Antibiotic prophylaxis duration ≥24 h after surgery (in hours)b | n/a | 27 (15) | |
Presence of wound drain installed during operation | 740 (65%) | 139 (90%) | < 0.001 |
Number of drains in surgical site | 1.1 (0.27) | 1.5 (0.53) | < 0.001 |
Number of drains in surgical site | < 0.001 | ||
1 | 686 (60%) | 74 (48%) | |
2 | 53 (4.7%) | 63 (41%) | |
3 | 1 (0.09%) | 2 (1.3%) | |
Drain 1 - Duration of drain (in hours) | 26 (11) | 43 (14) | < 0.001 |
Drain 2 - Duration of drain (in hours) | 32 (16) | 44 (10) | < 0.001 |
Cumulative drain output (of all drains) (in ml) | 131 (147) | 224 (223) | < 0.001 |
Post-operative transfusion of concentrated red blood cells | 11 (0.97%) | 2 (1.3%) | 0.66 |
Other transfusion (platelet concentrate, fresh frozen plasma, albumin) | 3 (0.26%) | 0 (0.00%) | 1.00 |
Record of NRS (Nutritional-Risk-score)c | 247 (22%) | 50 (32%) | 0.004 |
Absolute NRS score | 1.9 (0.85) | 2.1 (1.0) | 0.13 |
Surgical site infection | 4 (0.35%) | 0 (0.00%) | 1.00 |