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Table 4 Comparison between the VS and non-VS groups (univariate analysis)

From: Risk factors associated with cervical spine lesions in patients with rheumatoid arthritis: an observational study

 

VS group (n = 31)

Non-VS group (n = 154)

P-value*

Sex (male:female)

4:27

2:146

0.11

Age (years) (IQR)

67 (63−72)

68 (61−75)

0.36

Age of onset (years) (IQR)

48 (38−56)

55 (44−66)

< 0.01

RA duration (years) (IQR)

18 (13−25)

9 (4−21)

< 0.01

CRP level (mg/dL) (IQR)

0.7 (0.4−1.5)

0.3 (0.1−1.0)

< 0.01

RF positive (n)

55 % (17/31)

64 % (98/154)

0.36

MMP3 positive (n)

61 % (19/31)

66 % (102/154)

0.60

DAS28-CRP (IQR)

2.9 (2.2−3.6)

2.2 (1.7−3.0)

0.55

RA stage III or IV (n)

97 % (30/31)

64 % (99/154)

< 0.01

Prednisolone (n)

68 % (21/31)

45 % (69/154)

0.02

MTX (n)

52 % (16/31)

65 % (100/154)

0.16

Biological agents (n)

42 % (13/31)

28 % (43/154)

0.12

BMD of the lumbar spine (IQR)

79 % (74−92)

82 (71−93)

0.66

BMD of the femoral neck (IQR)

60 % (49–67)

68 (60–77)

0.04

Previous joint surgery (n)

68 % (21/31)

26 % (40/154)

< 0.01

  1. BMD bone mineral density, CRP C-reactive protein, DAS28-CRP Disease Activity Score based on C-reactive protein, MTX methotrexate, RA rheumatoid arthritis, VS vertical subluxation, IQR interquartile range
  2. *The P-value was calculated using the Fisher exact test, Mann−Whitney U test, and Student t-test, or chi-square test