Fig. 1
From: Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level
Age-related trabecular bone loss in mice. Femur (a), tibia (c) and L1 vertebrae (e) were harvested from 6- and 18-month-old mice. Micro-CT was employed to evaluate the trabecular bone microstructure. Trabecular bone parameters including BV/TV, Tb. N, and Tb. Sp were quantified according to micro-CT scans. Representative 3D reconstruction images of trabecular bone in the distal femur (b), proximal tibia (d), and L1 vertebrae (f) were displayed. Serum was prepared from peripheral blood of 6- and 18-month-old mice. ELISA was employed to quantify the levels of bone turnover markers including CTX-1 and P1NP (g). Data were shown as the means ± SD. *: p < 0.05, **: p < 0.01, ***: p < 0.001, 18 mo vs. 6 mo