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Table 1 Two-way ANOVA and mixed-effects model results for behavioral changes

From: Key indicators of repetitive overuse-induced neuromuscular inflammation and fibrosis are prevented by manual therapy in a rat model

Sonotrack Vocalization, means across weeks assayed using 2-way ANOVAs
  Treatment Group (TASK vs C) Significant Interactions
Mean # calls F(1,25) = 0.21, p = 0.65 F(1,25) = 0.15, p = 0.70 None
Mean length of calls F(1,24) = 0.21, p = 0.54 F(1,24) = 0.008, p = 0.87 None
Mean frequency of calls F(1,24) = 0.42, p = 0.54 F(1,24) = 1.20, p = 1.23 None
Cold Temperature Sensitivity, assessed in Week 12, assayed using a linear mixed-effects model
Treatment Group Temperature Significant Interactions
F(1,72) = 7.91, p = 0.006 F(1,80) = 10.50, p = 0.002 F(4,80) = 8.84, p < 0.0001 Treatment x Group: F(1,72) = 6.75, p = 0.01
Reflexive Grip Strength, assessed every 3 weeks, assayed using a mix-effects model with repeated measures
Treatment Group Week Significant Interactions
F(1,49) = 10.93; p = 0.002 F(1,49) = 6.83; p = 0.01 F(4,190) = 0.93, p = 0.45 Treatment x Group: F(1,49) = 4.98, p = 0.03
Sits in Corner/ Task Avoidance, assessed every 3 weeks, assayed using a mix-effects model with repeated measures
Treatment Group Week Significant Interactions
F(1,36) = 5.02, p = 0.03 N/A F (5, 48) = 1.27, p = 0.29 None