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Table 1 Two-way ANOVA and mixed-effects model results for behavioral changes

From: Key indicators of repetitive overuse-induced neuromuscular inflammation and fibrosis are prevented by manual therapy in a rat model

Sonotrack Vocalization, means across weeks assayed using 2-way ANOVAs

 

Treatment

Group (TASK vs C)

Significant Interactions

Mean # calls

F(1,25) = 0.21, p = 0.65

F(1,25) = 0.15, p = 0.70

None

Mean length of calls

F(1,24) = 0.21, p = 0.54

F(1,24) = 0.008, p = 0.87

None

Mean frequency of calls

F(1,24) = 0.42, p = 0.54

F(1,24) = 1.20, p = 1.23

None

Cold Temperature Sensitivity, assessed in Week 12, assayed using a linear mixed-effects model

Treatment

Group

Temperature

Significant Interactions

F(1,72) = 7.91, p = 0.006

F(1,80) = 10.50, p = 0.002

F(4,80) = 8.84, p < 0.0001

Treatment x Group: F(1,72) = 6.75, p = 0.01

Reflexive Grip Strength, assessed every 3 weeks, assayed using a mix-effects model with repeated measures

Treatment

Group

Week

Significant Interactions

F(1,49) = 10.93; p = 0.002

F(1,49) = 6.83; p = 0.01

F(4,190) = 0.93, p = 0.45

Treatment x Group: F(1,49) = 4.98, p = 0.03

Sits in Corner/ Task Avoidance, assessed every 3 weeks, assayed using a mix-effects model with repeated measures

Treatment

Group

Week

Significant Interactions

F(1,36) = 5.02, p = 0.03

N/A

F (5, 48) = 1.27, p = 0.29

None