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Table 1 Demographic and clinical characteristics of the two study groups

From: Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson’s disease: a multi-institutional retrospective cohort study

 

PD+ group

PD− group

p-value

Cases, n

27

206

Age at surgery (years)

70.6 ± 6.3

72.5 ± 8.5

0.18

Sex (male/female, n)

5/22

32/174

0.58

BMI

22.8 ± 4.2

23.2 ± 3.7

0.59

BMD (T-score)

−1.900 ± 1.249

− 1.863 ± 0.924

0.93

Medications for PD

 Dopamine precursors (yes/no)

23/4 (85.2%)

 Dopamine agonists (yes/no)

8/19 (29.6%)

 Monoamine oxidase type B inhibitors (yes/no)

6/21 (22.2%)

 Other

4/23 (14.8%)

Medical comorbidities

 Diabetes (yes/no)

1/26 (3.7%)

22/184 (10.7%)

0.49

 Rheumatoid arthritis (yes/no)

0/27

9/197 (4.4%)

0.60

 Renal dysfunction (yes/no)

0/27

19/187 (9.2%)

0.14

 Cardiovascular disease (yes/no)

2/25 (7.4%)

26/180 (12.6%)

0.75

 Cerebrovascular disease (yes/no)

5/22 (18.5%)

14/192 (6.8%)

0.053

 Respiratory disease (yes/no)

0/27

21/185 (10.2%)

0.14

Follow-up duration (months)

50.3 ± 16.2

49.0 ± 14.1

0.68

Number of fixed levels

9.3 ± 2.6

7.8 ± 1.9

0.006

3CO (yes/no)

17/10

100/106

0.14

Etiology (post fracture/degenerative/previous lumbar fusion)

10/15/2

21/133/52

0.001

Fix to sacrum (yes/no)

22/5 (81.5%)

174/32 (84.1%)

0.78

Pre SVA (mm)

196.0 ± 63.7

135.4 ± 69.9

< 0.001

Pre LL (°)

2.1 ± 19.3

3.5 ± 20.5

0.75

Pre TLK (°)

18.1 ± 16.0

19.2 ± 17.0

0.28

Pre TK (°)

24.1 ± 15.4

27.4 ± 20.0

0.37

Pre SS (°)

17.1 ± 8.0

14.7 ± 11.4

0.34

Pre PT (°)

36.6 ± 8.6

34.5 ± 13.2

0.47

PI (°)

53.6 ± 9.6

49.8 ± 9.1

0.088

  1. 3CO Three-column osteotomy, BMD Bone mineral density, BMI Bone mass index, LL Lumbar lordosis, PD Parkinson’s disease, PI Pelvic incidence, PT Pelvic tilt, SS Sacral slope, SVA Sagittal vertical axis, TK Thoracic kyphosis.