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Table 1 Study characteristics

From: Diagnostic accuracy of sensory and motor tests for the diagnosis of carpal tunnel syndrome: a systematic review

Author/year/ study design

Country

n-hands

n-individuals

n-CTS

Diagnostic tool(s)

Reference standard

Borg & Lindblom [20] /1988/ Prospective cross-sectional

Sweden

33

22

22

QST consisted of vibrometry, tactile thresholds, Von Frey hairs, 2PD, graphesthesia, warm and cold thresholds

A combined battery of tests

Buch-Jaeger & Foucher [21] / 1994/ Prospective cross-sectional

France

172

112

112

Vibratory sensibility, static 2PD, SWMFs

NCS

Dale et al. [8] /2011 / Prospective cross-sectional

USA

NR

1108

NR

SWMFs

Modified Katz Hand Diagram; NCS; The Consensus Criteria CTS Case Definition

Franzblau et al. [22] /1993/ Prospective cross-sectional

USA

260

130

22

Vibration, hand grip strength, palmar pinch grip

NCS; NCS+ surveillance symptom definitions for CTS; Physical examination + surveillance symptom definitions for CTS

Katz et al. [23] /1990/ Retrospective cross sectional

USA

165

110

44

2PD

NCS

Kucukakkas & Yurdakul [7]/ 2019/ Prospective cross-sectional

Turkey

463

463

226

Thenar atrophy, 2PD

NCS

Kuhlman et al. [24] /1997/ Prospective cross-sectional

USA

228

143

142

Hypoesthesia, APB weakness

NCS

MacDermid et al. [25] /1994/ Prospective cross-sectional

Canada

78

39

23

SWMFs

Clinical profile of CTS + NCS

MacDermid et al. [26] /1997/ Prospective cross-sectional

Canada

84

42

36

Vibration, pinch grip strength, SWMFs

NCS + positive clinical examination

Makanji et al. [11] /2013/ Prospective cohort

USA

NR

88

65

Thenar atrophy, thumb abduction weakness

NCS

Naranjo et al. [9] /2007/ Prospective cross-sectional

Spain

105

68

80

Thenar atrophy

NCS

Pagel et al. [27] /2002/ Prospective cross-sectional

Portland

NR

113

60

SWMFs

NCS

Raudino [28] /2000/ Prospective cross-sectional

Italy

140 hands

83

83

Hypoesthesia, thumb abduction Weakness

NCS

Sartorio [10] /2017/ Prospective cross-sectional

Italy

NR

80

80

Functional dexterity test

NCS

Szabo et al. [29] /1999/ Prospective cross-sectional

USA

CTS = 87

other diagnoses of UE = 90

100

87

SWMFs, grip strength

NCS

Yildirim & Gunduz [6] /2015/ Retrospective cross-sectional

Turkey

124

62

49

SWMFs

NCS

  1. List of abbreviations: ROB risk of bias, 2PD two-point discrimination, SWMFs Semmes-Weinstein monofilaments, APB Abductor Pollicis Brevis, NCS nerve conduction studies, QST quantitative sensory testing, NR not reported, CTS carpal tunnel syndrome, ROB risk of bias