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Table 1 modified Mankin score (criteria for histological evaluation)

From: A novel method to establish the rabbit model of knee osteoarthritis: intra-articular injection of SDF-1 induces OA

Item

Grade/classification

Grade

Structural intergrity

Normal

0

Irregular Surface

1

Pannus formation

2

Fissures into transitional layer

3

Fissures into emmiting layer

4

Fissures into calcified layer

5

Complete disorganization

6

Cells Normal

0

Hypercellularity

1

Cloning

2

Hypocellularity

3

Hematoxylin-eosin staining

Normal

0

Slight reduction

1

Moderate reduction

2

Severe reduction

3

No dye noted

4

Tidemark intergrity

Normal

0

Disruption

1