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Table 1 modified Mankin score (criteria for histological evaluation)

From: A novel method to establish the rabbit model of knee osteoarthritis: intra-articular injection of SDF-1 induces OA

Item Grade/classification Grade
Structural intergrity Normal 0
Irregular Surface 1
Pannus formation 2
Fissures into transitional layer 3
Fissures into emmiting layer 4
Fissures into calcified layer 5
Complete disorganization 6
Cells Normal 0
Hypercellularity 1
Cloning 2
Hypocellularity 3
Hematoxylin-eosin staining Normal 0
Slight reduction 1
Moderate reduction 2
Severe reduction 3
No dye noted 4
Tidemark intergrity Normal 0
Disruption 1