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Table 4 Parameters related to diabetic osteoporosis across quartiles of circulating BNP levels in patients with T2DM

From: Association of circulating B-type natriuretic peptide with osteoporosis in a Chinese type 2 diabetic population

Variables

 

Circulating BNP quintiles

 

P Value

Q1

(n = 78)

Q2

(n = 79)

Q3

(n = 79)

Q4

(n = 78)

Age (years)

59.59 ± 9.10

64.04 ± 9.91**

68.11 ± 8.89**##

68.53 ± 9.89**##

0.000

LS BMD (g/cm2)

0.998 ± 0.154

0.995 ± 0.189

0.968 ± 0.183

0.942 ± 0.173*

0.151

LS T score

− 0.922 ± 0.155

−0.959 ± 0.189

−1.204 ± 0.184

−1.434 ± 0.175

0.144

FN BMD (g/cm2)

0.844 ± 0.129

0.797 ± 0.139 *

0.764 ± 0.125**

0.733 ± 0.121**##

0.000

FN T score

−1.075 ± 0.120

−1.415 ± 0.124 *

− 1.599 ± 0.106 **

−1.881 ± 0.110 **##

0.000

TH BMD (g/cm2)

0.787 ± 0.124

0.755 ± 0.136

0.713 ± 0.127 **#

0.680 ± 0.113 **##

0.000

TH T score

−1.460 ± 0.103

−1.718 ± 0.113

−2.039 ± 0.110** ##

−2.274 ± 0.098**##

0.000

Fragility fractures (n, %)

5 (6.41%)

7 (8.86%)

4 (5.06%)

9 (11.54%)

0.359

Osteoporosis (n, %)

18 (23.08%)

28 (35.44%)

36 (45.57%)*

39 (50.00%)* *

0.003

Osteopenia (n, %)

31 (39.74%)

34 (43.04%)

30 (37.97%)

25 (32.05%)

0.551

  1. Data are mean ± SD. vs. Q1, *P < 0.05, **P < 0.01; vs. Q2, #P < 0.05,##P<0.01