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Table 2 LMEM results, change in muscle fat fraction scores from baseline to follow-up. Separate models run for each leg compartment fat fraction score, where beta coefficient corresponds to time from baseline to follow-up

From: Longitudinal study of MRI and functional outcome measures in facioscapulohumeral muscular dystrophy

Muscle fat fraction score

Beta [95% CI]

P-value

Reference:

Median [IQR] Score at baseline

IQR change in Score from baseline to follow-up

Muscle Fat Fraction Burden Index

0.35 [0.15, 0.54]

<.001

2.90 [1.54, 5.79]

[−0.12, 0.62]

DA leg compartment score

0.00 [−0.03, 0.04]

0.78

0.16 [0.09, 1.14]

[−0.06, 0.02]

DP leg compartment score

0.12 [0.01, 0.22]

0.026

1.00 [0.48, 2.74]

[−0.15, 0.20]

PA leg compartment score

0.12 [0.06, 0.18]

<.001

0.55 [0.34, 0.92]

[−0.03, 0.18]

PP leg compartment score

0.11 [0.04, 0.18]

0.001

0.76 [0.14, 1.45]

[−0.03, 0.10]