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Table 3 NGS, bacterial culture and serum biomarker test results

From: Diagnostic value of next-generation sequencing to detect periprosthetic joint infection

 

Infection group

Non-infection group

P value

CRP (mg/dL)

18.3 (8.9–32.2)

5.7 (3.7–10.8)

0.001a

ESR (mm/h)

32.3 (11.7–50.5)

17.2 (12.6–22.8)

0.099a

IL-6(pg/ml)

16.8 (9.5–37.6)

8.4 (3.3–15.5)

0.007a

PCT (ng/mL)

3.5 (0.3–4.8)

0.2 (0.1–0.3)

0.001a

D-Dimer (mg/L)

0.6 (0.2–1.9)

0.5 (0.2–0.9)

0.479a

NGS

  

< 0.001b

 +

14 (93.3)

2 (10)

 

 -

1 (6.7)

18 (90)

 

Bacterial culture

  

0.011b

 +

7 (46.7)

1 (5)

 

 _

8 (53.3)

19 (95)

 
  1. aMann-Whitney U test, bFisher exact test, + positive, - negative