Fig. 2

Correlation between plasma IL-21 level with DAS score. IL-21 levels were measured by ELISA in all RA patients and correlated with the DAS score of RA patients. A positive correlation was observed among IL-21 levels and DAS scores (a). Further, RA subjects were subcategorized in to four groups based on DAS scores such as remission [DAS 28 < 2.6 (n = 52)], low activity [DAS 28, ≥2.6 to < 3.2 (n = 12)], medium activity [DAS 28, ≥3.2 to ≤5.1 (n = 79)] and high activity [DAS 28, > 5.1 (n = 68)]. Data represented the mean of IL-21 levels (ng/mL) ± SD and were compared using ANOVA with Tukey’s post-test. A P-value of less than 0.05 was taken as statistically significant