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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: The attenuation of insulin-like growth factor signaling may be responsible for relative reduction in matrix synthesis in degenerated areas of osteoarthritic cartilage

Fig. 3

The expression of IGF-BPs in OA and control cartilage. The expression of six IGFBP genes was determined in the respective cartilage zones of control (Control) and osteoarthritic cartilage (OA). The IGFBP1 (a), IGFBP2 (b), IGFBP3 (c), IGFBP4 (d), IGFBP5 (e) and IGFBP6 (f) expression is shown as described in Fig. 1. Preserved and Degenerated indicate macroscopically intact and degenerated areas of OA cartilage, respectively. S, M and D denote superficial, middle and deep cartilage zones, respectively, which are shown by open, shaded and closed bars, respectively. Values are the mean and SE of 7–19 samples. a and b indicate p < 0.05 compared to the corresponding zone in control cartilage, or compared to the corresponding zone in preserved areas of OA cartilage, respectively

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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