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Fig. 7 | BMC Musculoskeletal Disorders

Fig. 7

From: Compressive mechanical stress enhances susceptibility to interleukin-1 by increasing interleukin-1 receptor expression in 3D-cultured ATDC5 cells

Fig. 7

Immunohistochemistry of TRPV4 and IL-1R. a, b) In 3D-cultured constructs in type-I collagen scaffold stained with toluidine blue, cells with cyclic compressive loading showed a round morphology as compared with cells without cyclic compressive loading. c-h) Immunofluorescent staining of TRPV4 (d and e) and IL-1R (g and h) revealed significant increases in TRPV4 (e) and IL-1R (h) immunoreactivities after cyclic compressive load was applied on the 3D-cultured constructs

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