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Table 3 Musculoskeletal markers of DM patients and controls

From: Myostatin and markers of bone metabolism in dermatomyositis

  DM
(n = 20)
Controls
(n = 20)
p-value
MSTN [ng/ml] 2.5 [1.9; 3.2] 1.9 [1.6; 2.3] < 0.05
FSTN [pg/ml] 1343 [929; 1856] 1232 [1093; 1433] n.s.
SOST [pmol/l] 28.9 [23.3; 34.4] 28.3 [24.4; 35.7] n.s.
Dkk 1 [pmol/l] 11.4 [6.9; 20.0] 31.8 [14.3; 50.6] < 0.01
PSTN [ng/ml] 3.2 [2.0; 5.8] 3.6 [2.6; 7.0] n.s.
RANKL/OPG 0.017 [0.005; 0.055] 0.030 [0.020; 0.048] n.s.
FGF23 [pmol/l] 2.17 [1.45; 3.26] 1.28 [0.79; 1.96] < 0.05
  1. MSTN Myostatin, FSTN Follistatin, SOST Sclerostin. Dkk 1 Dickkopf 1, PSTN Periostin, RANKL Receptor activator nuclear factor kB; OPG Osteoprotegerin, FGF23 Fibroblast growth factor 23