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Table 1 Baseline characteristics of study participants

From: The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial

 

Total

(n = 200)

PRP

(n = 52)

PRGF

(n = 51)

HA

(n = 49)

Ozone

(n = 48)

Baseline characteristics

 Age (yr),Mean ± SD

56.9 ± 6.3

56.09 ± 6.0

56.07 ± 6.3

57.91 ± 6.7

57.60 ± 6.1

 Sex (Male/Female)

61/139

13/39

14/37

12/37

12/36

 BMI (kg/m2), Mean ± SD

28.24 ± 2.8

27.41 ± 2.6

27.50 ± 2.1

27.46 ± 2.2

27.01 ± 1.9

 Duration of pain (yr), Mean ± SD

4.41 ± 2.2

4.44 ± 2.3

4.9 ± 2.7

3.86 ± 1.6

4.42 ± 2.1

 Side of injection (left/right)

93/107

22/30

18/33

28/21

25/23

 Degree of osteoarthritis (2/3)

108/92

26/26

28/23

27/22

27/21

 History physiotherapy, n(%)

119 (59.5)

29 (55.8)

36 (70.6)

26 (53.1)

28 (42.3)

 History injection, n(%)

92 (46.0)

22 (44.3)

25 (49.0)

24 (49.0)

21 (58.3)

 Pain during injection, Mean ± SD

2.43 ± 2.0

2.80 ± 2.2

3.07 ± 2.6

1.81 ± 1.3

1.95 ± 1.18

Outcome measures

 VAS, Mean ± SD

8.03 ± 1.2

7.92 ± 1.0

7.90 ± 1.3

8.22 ± 1.1

8.10 ± 1.0

WOMAC, Mean ± SD

 Pain

9.54 ± 1.6

9.69 ± 1.3

9.72 ± 1.7

9.44 ± 1.6

9.29 ± 1.8

 Function

30.68 ± 7.3

30.19 ± 6.4

30.54 ± 7.6

31.02 ± 8.8

31.00 ± 6.1

 Stiffness

2.73 ± 1.3

2.84 ± 1.1

2.84 ± 1.6

2.71 ± 1.1

2.50 ± 1.1

 Total

42.85 ± 9.2

42.73 ± 7.7

43.11 ± 9.6

42.75 ± 11.1

42.79 ± 8.2

LEQ, Mean ± SD

 Pain

5.31 ± 1.0

5.17 ± 1.0

5.13 ± 1.1

5.55 ± 0.9

5.41 ± 1.0

 Walk

1.65 ± 0.8

1.65 ± 0.6

1.66 ± 0.8

1.71 ± 0.9

1.56 ± 0.7

 ADL

5.71 ± 0.7

5.75 ± 0.6

5.71 ± 0.7

5.70 ± 0.8

5.67 ± 0.7

 Total

12.65 ± 2.0

12.58 ± 1.6

12.62 ± 2.1

12.76 ± 2.2

12.65 ± 2.0

  1. Abbreviations: SD standard deviation; PRGF plasma rich in growth factor; PRP platelet-rich plasma; HA hyaluronic acid; VAS visual analog scale; WOMAC Western Ontario and McMaster Universities Osteoarthritis Index; LEQ Lequesne Index