Skip to main content

Table 2 Postoperative early-phase outcomes

From: The comparative efficacies of intravenous administration and intra-articular injection of tranexamic acid during anterior cruciate ligament reconstruction for reducing postoperative hemarthrosis: a prospective randomized study

 

IV group

IA group

Placebo group

F/χ2 value

p value

Day 1

 Drain output volume (mL)

78.5 ± 38.4c

63.3 ± 31.8c

120.1 ± 57.4a, b

21.522

< 0.001

Week 1

 VAS score

2.7 ± 1.0c

2.4 ± 1.1c

3.5 ± 0.9a, b

12.793

< 0.001

 Patellar circumference (cm)

18.1 ± 5.0c

19.4 ± 6.2c

24.6 ± 7.0a, b

12.549

< 0.001

 Hemarthrosis grade, 0/1/2/3/4, n.

9/16/8/5/2c

8/16/11/4/1 c

0/5/11/15/9a, b

35.221

< 0.001*

Week 2

 VAS score

2.3 ± 1.1c

2.2 ± 1.1c

3.1 ± 1.1a, b

8.343

< 0.001

 Patellar circumference (cm)

11.2 ± 4.2c

10.0 ± 3.4c

16.0 ± 5.4a, b

20.446

< 0.001

 Hemarthrosis grade, 0/1/2/3/4, n.

13/19/6/2/0c

13/18/8/1/0c

4/16/16/4/0a, b

13.186

0.031

Week 4

 VAS score

1.7 ± 1.2

1.7 ± 1.2

1.9 ± 1.4

0.265

0.768

 Patellar circumference (cm)

5.7 ± 3.1

5.3 ± 3.2

5.8 ± 3.9

0.258

0.773

 Hemarthrosis grade, 0/1/2/3/4, n.

16/17/5/2/0

18/17/2/3/0

11/18/8/3/0

5.742

0.455

 Lysholm score

80.9 ± 11.8

82.1 ± 11.1

78.6 ± 10.6

1.026

0.362

  1. *Fisher-Freeman-Halton exact test;
  2. aSignificant difference compared to the IV group (p < 0.05)
  3. bSignificant difference compared to the IA group (p < 0.05)
  4. cSignificant difference compared to the placebo group (p < 0.05)