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Fig. 5 | BMC Musculoskeletal Disorders

Fig. 5

From: Early patellofemoral articular cartilage degeneration in a rat model of patellar instability is associated with activation of the NF-κB signaling pathway

Fig. 5

SafraninO and fast green staining in cartilage of rats. CON and PI group respectively: a, b 4 weeks; c, d 8 weeks; and (e, f) 12 weeks. (A′–F′) images at a higher magnification of boxed areas in (a–f). In the PI group, safranin O and fast green histochemical staining showed that the surface of the cartilage was irregular and destroyed at 8, 12 weeks after surgery(the thin black arrow in d, f ). In D′, F′, we observed cell aggregation(the thick black arrow), and the number of chondrocytes in the superficial and middle zone was significantly reduced, which was consistent with OA. g estimating cell numbers of the superficial and middle zone; h OARSI score for articular cartilage: increased OARSI score and decreased cell number were observed in the PI Group at 4,8, and 12 weeks after surgery. *p < 0.05 (CON Group, control group; PI Group, patellar instability group)

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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