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Table 1 Comparison of clinical data of the renal tubular acidification dysfunction group and the normal function group (X±S)

From: Evaluating distal renal tubular acidification function in primary hyperparathyroidism and its effects on bone mineral density

Variable Abnormal acidification group (41) Normal acidification function group (34) P
Sex (male/female) 13/28 8/26 0.432 (χ2)
Medical history (y) 0.25 (1, 5.5) 0.33 (1, 5) 0.881 (Non-parametric)
Age, y 61.1 ± 12.0 56.8 ± 11.0 0.116
BMI, kg/m2 24.2 ± 4.85 24.74 ± 3.84 0.602
Albumin, g/L 41.24 ± 3.86 40.79 ± 3.54 0.604
Albumin-corrected serum calcium, mmol/L 2.80 ± 0.39 2.84 ± 0.31 0.635
Serum phosphate, mmol/L 0.69 ± 0.17 0.79 ± 0.18 0.017
Serum potassium, mmol/L 3.85 ± 0.50 4.08 ± 0.51 0.061
Serum chloride (mmol/L) 107.55 ± 3.45 107.23 ± 3.99 0.717
Serum sodium (mmol/L) 141.06 ± 2.70 142.24 ± 1.71 0.062
Serum magnesium (mmol/L) 0.83 ± 0.11 0.86 ± 0.07 0.220
Serum creatinine, umol/L 58 (47.5, 73) 58 (42.75, 73.25) 0.447 (Non-parametric)
AkP (U/L) 125 (91.5, 231.5) 103.5 (67, 157.75) 0.075 (Non-parametric)
PTH (pmol/L) 59.4 (24.65, 130) 36.1 (17.17, 64.02) 0.061 (Non-parametric)
25OHD (nmol/L) 34.5 (21.4, 64.02) 25.5 (20.45, 32.66) 0.020 (Non-parametric)
Urine PH (4.5-6.5) 6.67±0.45 5.78±0.42 0.000
Urine HCO3-(0-12.44mmol/L) 5.50 (3.35, 10.90) 4.50 (2.87, 5.90) 0.231 (Non-parametric)
Urine TA (9.57-150mmol/L) 4.45 ± 2.83 11.91 ± 4.39 0.000
Urine NH4+(25.84-200mmol/L) 16.48 ± 5.57 25.62 ± 5.89 0.000
Blood gas PH (7.35-7.45) 7.40 ± 0.28 7.40 ± 0.21 0.266
PCO2 (mmHg) 36.76 ± 5.12 37.51 ± 4.84 0.519
HCO3-(mmol/L) 23.20 ± 3.15 23.87 ± 2.63 0.327
BE (mmol/L) -1.80 (-3.3, 0.82) -0.77 (-1.92, 1.00) 0.165 (Non-parametric)
Urinary calcium, (mmol/24h) 8.30 ± 3.30 7.98 ± 3.64 0.280
Urinary phosphate, (mmol/24h) 18.8 ± 7.34 20.4 ± 8.34 0.389
Urinary potassium, (mmol/24h) 18.65 ± 7.11 20.40 ± 8.34 0.331
Urine sodium (mmol/24h) 138.46 (93.01, 205.75) 197.6 (157.59, 228.51) 0.161 (Non-parametric)
Urine magnesium (mmol/24h) 2.85 (1.84, 3.63) 2.7 (2.19, 3.48) 0.898 (Non-parametric)
OC (ng/ml) 60.06 (29.49, 125.25) 59.61 (33.58, 131.30) 0.903 (Non-parametric)
CTX (ng/ml) 0.99 (0.65, 1.86) 1.18 (0.80, 2.49) 0.225 (Non-parametric)
PINP (ng/ml) 70 (45.28, 125.25) 74.28 (41.09, 103.80) 0.709 (Non-parametric)
Kidney stones (with/without) 19/22 12/22 0.333 (χ2)
Fracture (with/without) 13/28 10/24 0.830 (χ2)