Skip to main content
Fig. 5 | BMC Musculoskeletal Disorders

Fig. 5

From: Long non-coding RNA CCHE1 participates in postoperative distant recurrence but not local recurrence of osteosarcoma possibly by interacting with ROCK1

Fig. 5

LncRNA CCHE1 silencing inhibited migration and invasion of cells of MG-63 and U2OS human osteosarcoma cell lines. LcRNA CCHE1 silencing and OCK1 overexpression were reached at 24 h after transfection (a). LncRNA CCHE1 silencing significant inhibited, while ROCK1 overexpression significantly promoted the migration (b) and invasion (c) of cells of both MG-63 and U2OS human osteosarcoma cell lines. In addition, ROCK1 overexpression attenuated the inhibitory effects of lncRNA CCHE1 on cancer cell migration and invasion (*, p < 0.05)

Back to article page