The efficacy of continuous versus single-injection femoral nerve block in Total knee Arthroplasty: a systematic review and meta-analysis

Table 1 Characteristics of included studies

Year/First author	Study design	Enrolled Sample number (G1/G2)	Comparing	Anesthesia	Regimen of first bolus in sFNB/cFNB	Regimen and rate of infusion in cFNB	Outcome measurement
Year/First author	Study design	Enrolled Sample number (G1/G2)	Comparing	Anesthesia	Regimen of first bolus in sFNB/cFNB	Regimen and rate of infusion in cFNB	a	b	c	d	e	f
2019 Angers	RCT	45/45	cFNB, sFNB	SA/GA	20 ml, 0.05% Ropi	0.15% Ropi, 7 ml/hr					V
2018 Dixit	RCT	44/41	cFNB, sFNB	SA	20-25 ml, 0.5% Ropi	0.2% Ropi, rate not mentioned	V	V	V	V	V	V
2015 Wyatt	RCT	42/42	cFNB, sFNB	SA/GA	20 ml, 0.25% Bupi	0.125% Bupi 10 ml/hr	V	V			V
2013 Chan	RCT	65/69	cFNB, sFNB	SA/GA	20 ml, 0.25% Bupi with 1:400,000 Epi	0.125% Bupi 4 ml/hr	V	V	V	V	V	V
2013 Albrecht	RCT	60/33	cFNB, sFNB	SA	sFNB: 30 ml, 0.375% Ropi with 1:400,000 Epi cFNB: 20 ml, 0.2% Ropi with 1:400,000 Epi	Ropi, 10 mg/hr. 10 mg bolus allowed every 30 mins	V	V	V	V		V
2010 Park	RCT	60/20	cFNB, sFNB	SA	20 ml, 0.125% Bupi with 1:200,000 Epi	0.125% Bupi 2,4,6 ml/hr	V	V	V	V
2006 Salinas	RCT	18/18	cFNB, sFNB	SA	30 ml, 0.375% Ropi with 1:400,000 Epi	0.2% Ropi 10 ml/hr	V	V	V	V	V
1996 Hirst	RCT	11/11	cFNB, sFNB	GA	20 ml, 0.5% Bupi with 1:200,000 Epi	0.125% Bupi 6 ml/hr	V	V	V	V		V

G1 group: study group (cFNB); G2 Group: control group (sFNB)
Outcome measure: a = VAS at 24 h b = VAS at 48 h, c = amount of analgesics consumed within 24 h, d = amount of analgesics consumed within 48 h, e = Length of hospital stay, f = nausea or vomiting event
FNB femoral nerve block; SA spinal anesthesia; GA general anesthesia
Bupi Bupivacaine; Epi Epinephrine; Ropi Ropivacaine

ISSN: 1471-2474