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Table 1 Characteristics of included studies

From: The efficacy of continuous versus single-injection femoral nerve block in Total knee Arthroplasty: a systematic review and meta-analysis

Year/First authorStudy designEnrolled Sample number (G1/G2)ComparingAnesthesiaRegimen of first bolus in sFNB/cFNBRegimen and rate of infusion in cFNB Outcome measurement
abcdef
2019 AngersRCT45/45cFNB, sFNBSA/GA20 ml, 0.05% Ropi0.15% Ropi, 7 ml/hr     V 
2018 DixitRCT44/41cFNB, sFNBSA20-25 ml, 0.5% Ropi0.2% Ropi, rate not mentioned VVVVVV
2015 WyattRCT42/42cFNB, sFNBSA/GA20 ml, 0.25% Bupi0.125% Bupi 10 ml/hr VV  V 
2013 ChanRCT65/69cFNB, sFNBSA/GA20 ml, 0.25% Bupi
with 1:400,000 Epi
0.125% Bupi
4 ml/hr
 VVVVVV
2013 AlbrechtRCT60/33cFNB, sFNBSAsFNB: 30 ml, 0.375% Ropi with 1:400,000 Epi
cFNB: 20 ml, 0.2% Ropi with 1:400,000 Epi
Ropi, 10 mg/hr.
10 mg bolus allowed every 30 mins
 VVVV V
2010 ParkRCT60/20cFNB, sFNBSA20 ml, 0.125% Bupi
with 1:200,000 Epi
0.125% Bupi
2,4,6 ml/hr
 VVVV  
2006 SalinasRCT18/18cFNB, sFNBSA30 ml, 0.375% Ropi
with 1:400,000 Epi
0.2% Ropi
10 ml/hr
 VVVVV 
1996 HirstRCT11/11cFNB, sFNBGA20 ml, 0.5% Bupi
with 1:200,000 Epi
0.125% Bupi
6 ml/hr
 VVVV V
  1. G1 group: study group (cFNB); G2 Group: control group (sFNB)
  2. Outcome measure: a = VAS at 24 h b = VAS at 48 h, c = amount of analgesics consumed within 24 h, d = amount of analgesics consumed within 48 h, e = Length of hospital stay, f = nausea or vomiting event
  3. FNB femoral nerve block; SA spinal anesthesia; GA general anesthesia
  4. Bupi Bupivacaine; Epi Epinephrine; Ropi Ropivacaine