Fig. 6

Immunostaining for a MMP9, b VEGF, c RUNX2, and d OCN, and e TRAP staining at the metaphyseal defect at day 14 after fracture in the aged wild-type (WT-aged) mice, aged Wnt/β-catenin activation (CA-aged) mice, and aged PTH activation (PTH-aged) mice. f TRAP-positive cells and g-j Quantification of the number of positive cells were performed. The results are expressed as the mean ± SD; n = 4 per group; ^*P < 0.05 and ^**P < 0.01