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Table 2 Association between serum zinc and knee chondrocalcinosis (n = 12,362)

From: Association between serum zinc and copper concentrations and copper/zinc ratio with the prevalence of knee chondrocalcinosis: a cross-sectional study

 

Tertiles of serum zinc (μmol/L)

P for trend

1 (≤ 12.1)

2 (12.2–14.2)

3 (≥ 14.3)

Total

 Knee chondrocalcinosis (%)

1.7

1.2

0.8

–

 N for kneea

8354

8285

8082

–

 Model 1 (95% CI)

1.00 (reference)

0.74 (0.50, 1.09)

0.56 (0.36, 0.86)

0.009

 Model 2 (95% CI)

1.00 (reference)

0.77 (0.52, 1.14)

0.59 (0.38, 0.91)

0.018

 Model 3 (95% CI)

1.00 (reference)

0.73 (0.49, 1.08)

0.54 (0.35, 0.84)

0.006

 Model 4 (95% CI)

1.00 (reference)

0.75 (0.51, 1.12)

0.56 (0.37, 0.87)

0.010

 Model 5 (95% CI)

1.00 (reference)

0.75 (0.51, 1.11)

0.58 (0.37, 0.88)

0.012

 Model 6 (95% CI)

1.00 (reference)

0.75 (0.50, 1.11)

0.56 (0.37, 0.87)

0.011

  1. Model 1 included age (40–49, 50–59, 60–69, ≥ 70 years), body mass index (< 28, ≥ 28 kg/m2) and sex (n = 12,362);
  2. Model 2 added serum iron (tertiles) on the basis of model 1 (n = 12,357);
  3. Model 3 added serum calcium (tertiles) on the basis of model 1 (n = 12,264);
  4. Model 4 added serum magnesium (tertiles) on the basis of model 1 (n = 12,362);
  5. Model 5 added serum copper (tertiles) on the basis of model 1 (n = 12,362);
  6. Model 6 added serum phosphorus (tertiles) on the basis of model 1 (n = 12,264)
  7. aThree right knees with K-L 4 grade were excluded for analysis (data from the contralateral knees were retained)
  8. N number, CI confidence interval