Table 1 The comparison of control subjects and patients with HIV
From: Trabecular bone scores in young HIV-infected men: a matched case-control study
Variables (N (%) or mean ± SD) | Control (N = 80) | HIV (N = 80) | P-value |
|---|---|---|---|
Demographic findings | |||
Age (years) | 39 ± 8 | 39 ± 8 | 0.693 |
BMI (kg/m2) | 24.9 ± 3.3 | 22.9 ± 3.0 | < 0.001 |
Currently smoking | 44 (55) | 36 (45.0) | 0.081 |
Alcohol ≥3 units/day | 3 (4) | 3 (4) | 1.000 |
Previous fracture | 1 (1) | 10 (12.5) | 0.009 |
Underlying disease | |||
Diabetes mellitus | 0 (0) | 3 (3.8) | 0.245 |
Hypertension | 0 (0) | 4 (5.0) | 0.120 |
Dyslipidemia | 0 (0) | 8 (10.0) | 0.028 |
Laboratory findings | |||
Urea nitrogen (mg/dl) | 13.9 ± 2.8 | 13.2 ± 3.5 | 0.154 |
Creatinine (mg/dl) | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.928 |
Calcium (mg/dl) | 9.1 ± 0.8 | 9.1 ± 0.3 | 0.470 |
Phosphorus (mg/dl) | 3.6 ± 1.5 | 3.3 ± 0.5 | 0.130 |
ESR (mm/h) | 7.4 ± 5.4 | 9.6 ± 9.0 | 0.081 |
Hemoglobin (g/dl) | 15.6 ± 1.1 | 15.3 ± 1.0 | 0.041 |
Platelet (103/μl) | 245 ± 59 | 228 ± 39 | 0.033 |
HIV-specific factors | |||
Duration since HIV diagnosis (days) | 2622.9 ± 1814.9 | ||
Nadir CD4 T-cell counts (cells/μl) | 349 ± 183 | ||
Current CD4 count (cells/μl) | 669 ± 271 | ||
Current proportion with plasma HIV-1 RNA viral load < 40 copies/ml | 75 (93.7%) | ||
On ART | 78 (97.5%) | ||
On TDF | 40 (50.0%) | ||
Current ART | |||
NNRTI-based | 28 | ||
PI-based | 29 | ||
Integrase inhibitor-based | 21 | ||
Duration of ART (days) | 677.9 ± 411.2 | ||