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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Intervertebral disc degeneration in mice with type II diabetes induced by leptin receptor deficiency

Fig. 3

Decreased the extend of Safranin-O staining in intervertebral disc of db/db mice indcued by leptin receptor knock out. a, b, c Representative safranin-O staining of mice intervertebral disc in WT, db/db and IGF-1 treated mice. d Quantitative measurements of the extend of Safranin-O staining in intervertebral disc in each group. (N = 5, triplicates per group). All data are reported as the mean ± s.d. Statistical significance was determined by three-way ANOVA and Student’s t-test. *P < 0.05(IGF-1 treated group compare to WT). #P < 0.05(db/db group compare to WT). aP < 0.05(IGF-1 treated compare to db/db group)

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