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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production

Fig. 3

Inhibitory effect of polyphyllin VII (PP7) on the resorption capability of osteoclasts. Panel a Image of resorption lacunae under light microscope. The resorption lacunae assay in the presence of various concentrations of polyphyllin VII (PP7) was performed as described in the methods. Panel b Average areas of resorption lacunae per well in the presence of various concentrations of polyphyllin VII (PP7). Vertical axis: pixel dimensions; horizontal axis: polyphyllin VII (PP7) concentrations (μM). * P < 0.05 as compared with the group treated with 0 μM of polyphyllin VII (PP7); the dotted line represents a regression line

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