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Table 1 Demographic characteristics of the study population

From: Low BASDAI score alone is not a good predictor of anti-tumor necrosis factor treatment efficacy in ankylosing spondylitis: a retrospective cohort study

 

Variables

(n=116)

Age at enrolment, years

33.9 (26.7–40.3)

Male sex

109 (94)

Disease duration, years

10.8 (5.3–15.5)

Follow-up duration, years

6.4 (4.5–7.1)

HLA B27 positivity

115 (99.1)

Peripheral joint involvement

52 (44.8)

History of psoriasis

2 (1.7)

History of uveitis

35 (30.2)

mSASSS

9.0 (6.0–25.9)

BASDAI

2.3 ± 0.9

ASDAS-CRP

2.0 ± 0.5

 High ASDAS-CRP (≥ 2.1)

45 (38.8)

ESR, mm/hr. (normal ≤ 20)

3.0 (2.0–6.0)

CRP, mg/dL (normal ≤ 0.3)

0.2 (0.2–0.2)

Use of anti-TNF agents

 Adalimumab

41 (35.3)

 Etanercept

34 (29.3)

 Infliximab

27 (23.3)

 Golimumab

14 (12.1)

Discontinuation of anti-TNF agent during follow up

13 (11.2)

 Lack/loss of efficacy

9 (69.2)

 Clinical remission

3 (23.1)

 Adverse event

1 (7.7)

  1. Numerical quantitative data were presented as the “mean ± SD” or “median (IQR)” and categorical data were presented as the “frequency (%)”
  2. SD standard deviation, IQR interquartile range, HLA B27 human leukocyte antigen B27, mSASSS modified Stoke Ankylosing Spondylitis Spinal Score, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, ASDAS Ankylosing Spondylitis Disease Activity Score, CRP C-reactive protein, ESR erythrocyte sedimentation rate, TNF tumor necrosis factor