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Table 1 Osteogenesis imperfecta (OI) patient characteristics, polysomnography findings, and self-evaluation of daytime sleepiness and depression

From: Positive airway pressure therapy for obstructive sleep apnea in patients with Osteogenesis imperfecta: a prospective pilot study

Patient

Age

(years)

OI type

BMI

kg/m2

AHI/hour

ESS

DEPS

PAP therapy

     

baseline

PAP therapy

baseline

PAP therapy

0=no treatment

1= PAP therapy

2=refused

3=no data

% of days with devise usage

Daily usage/hours

1

29

I

23.4

11.4

9

NA

5

NA

0

  

2

49

I

33.6

29.5

13

13

14

19

1

91

4.3

3

69

I

20.3

21.0

5

NA

3

NA

1

  

4

72

I

21.1

23.1

6

NA

NA

NA

2

  

5

77

I

24.9

14.2

6

NA

9

NA

1

100

7.0

6

27

III

37.6

21.4

11

3

NA

1

1

50

7.3

7

34

III

62.1

9.0

1

NA

NA

NA

3

  

8

40

III

29.5

10.0

5

3

21

6

1

100

8.5

9

46

III

33.4

7.5

4

3

7

4

2

  

10

52

III

43.0

45.1

11

9

6

6

1

73

4.4

11

71

III

32.1

24.8

14

13

11

11

1

14

4.0

12

44

IV

23.7

11.3

6

NA

23

NA

3

  

13

45

IV

26.0

11.7

NA

12

NA

23

1

100

7.1

14

49

IV

29.0

18.5

4

3

1

3

1

100

10.0

15

52

IV

22.4

5.8

11

12

6

9

1

  

16

58

IV

26.4

24.9

1

3

13

7

1

100

7.4

17

63

IV

26.7

10.7

3

7

4

10

1

  

18

35

NA

37.2

111.0

NA

2

NA

NA

1

100

9.2

19

46

NA

31.6

17.0

NA

NA

NA

NA

2

  

20

65

NA

31.3

85.0

5

5

2

7

1

100

7.0

Average

51

 

30.4

26.1

7

7

9

9

 

84

6.8

SD

15

 

9.6

27.4

4

4

7

6

 

28

2.0

Range

27-77

 

20.3-62.1

5.8-111

1-14

2-13

1-21

1-19

 

50-100

4-10

  1. Abbreviations: OI type I: Mild, non-deforming; OI type III: Moderate to severe, progressively deforming; OI type IV: Moderate with wide variety in severity; Height Z-score: relative height as SD from gender-specific population median; BMI body mass index, AHI apnea and hypopnea index, ESS Epworth sleepiness scale (0–24 score scale), DEPS Depression Scale (0–30 score scale), PAP positive airway pressure, NA not available
  2. Self-evaluation of daytime sleepiness and depression was conducted at baseline and with PAP therapy. The pre-treatment data is partly overlapping with Arponen et al. [7]