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Table 2 Summary of key elements of assessed studies

From: Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery

Authors Year Journal Country Level of Evidence Study type Study Design Length of Follow Up (months)
Akasaki et al. [35] 2015 Arthritis Rheumatol United States (California) 3 Diagnostic Case control none
aus dem Siepen et al. [36] 2019 Clin Res Cardiol Germany 3 Diagnostic Retrospective comparative 29 ± 29
Bishop et al. [15] 2018 Amyloid United States (Maryland) 3 Diagnostic Retrospective comparative none
Fernandez Fuertes et al. [37] 2017 Med Clin (Barc) Spain 3 Diagnostic Prospective cohort* 36
Geller et al. [38] 2017 JAMA United States (Massachusetts) 3 Diagnostic Case control none
Gies et al. [39] 1996 Clin Neuropathol Germany 4 Diagnostic Case series none
Gioeva et al. [14] 2013 Amyloid Germany 4 Diagnostic Case series none
Gu et al. [23] 2014 J Zhejiang Univ Sci B China 3 Diagnostic Case control none
Kyle et al. [40] 1992 Am J Clin Pathol United States (Minnesota) 4 Diagnostic Case series 168
Nakamichi et al. [41] 1996 Muscle Nerve Japan 4 Diagnostic Case series 56
Niggemeyer et al. [42] 2011 Arch Orthop Trauma Surg Germany 4 Diagnostic Case series none
Rubin et al. [27] 2017 Amyloid United States (New York) 3 Diagnostic Retrospective comparative none
Samões et al. [43] 2017 Amyloid Portugal 4 Diagnostic Case series 38.4
Scott et al. [44] 2019 Plast Reconstr Surg United States (Arizona) 4 Diagnostic Case series none
Sekijima et al.18 2011 Hum Pathol Japan 3 Diagnostic Case control none
Sperry et al. [45] 2018 J Am Coll Cardiol United States (Ohio) 2 Diagnostic Prospective cohort next phase of study
Stein et al. [46] 1987 Virchows Arch A Pathol Anat Histopathol Germany 4 Diagnostic Case series none
Sueyoshi et al. [13] 2011 Hum Pathol Japan 4 Diagnostic Case series none
Takanashi et al. [25] 2013 Amyloid Japan 4 Diagnostic Case series none
Uchihara et al. [47] 2018 Pathol Res Pract Japan 4 Diagnostic Case series none
Westermark et al. [20] 2014 Ups J Med Sci Sweden 4 Diagnostic Case series none
Yanagisawa et al. [21] 2015 Mod Pathol Japan 4 Diagnostic Case series none
Yanagisawa et al. [26] 2016 Amyloid Japan 4 Diagnostic Case series none
Zegri-Reiriz et al. [48] 2019 J Cardiovasc Transl Res Spain 3 Diagnostic Prospective cohorta none
  1. ano consistently applied reference standard