Skip to main content

Table 5 Joint effect of keloid and comorbidities on the risk of osteoporosis

From: The association between keloid and osteoporosis: real-world evidence

Variables   N Osteoporosis Rate Adjusted HR (95% CI)
Keloid Hyperlipidemia     
No No 30,191 251 0.56 1.00 (Reference)
No Yes 4197 336 5.58 1.37 (1.13–1.65)**
Yes No 6826 60 1.56 2.48 (1.85–3.33)**
Yes Yes 1771 118 11.07 3.75 (2.93–4.80)**
Keloid Chronic liver disease     
No No 29,441 338 0.77 1.00 (Reference)
No Yes 4947 249 3.45 1.19 (1.00–1.43)#
Yes No 6411 81 2.28 2.34 (1.82–3.01)**
Yes Yes 2186 97 7.15 3.56 (2.77–4.58)**
Keloid Stroke     
No No 33,858 501 0.99 1.00 (Reference)
No Yes 530 86 11.85 1.45 (1.14–1.85)*
Yes No 8335 143 3.01 2.59 (2.13–3.16)**
Yes Yes 262 35 23.55 4.21 (2.94–6.03)**
Keloid Depression     
No No 32,114 467 0.98 1.00 (Reference)
No Yes 2274 120 3.62 1.18 (0.96–1.46)#
Yes No 7531 125 2.92 2.45 (1.98–3.02)**
Yes Yes 1066 53 8.46 3.92 (2.90–5.29)**
  1. a Rate, incidence rate in per 1000 person-years; 95% CI 95% Confidence interval; HR Hazard ratio
  2. * P< 0.01, **P< 0.001, # non-significant