From: The association between keloid and osteoporosis: real-world evidence
Variables | Keloid | P value | |
---|---|---|---|
 | Yes | No |  |
 | N=8597 | N=34,388 |  |
Osteoporosis patients, n (%) | 178 (2.07) | 587 (1.71) | < 0.05 |
Period of developing osteoporosis median (IQRa), years | 3.0 (1.2–5.7) | 6.7 (4.1–10.2) | < 0.001 |
Mean age of osteoporosis (SDb), years | 56.3 (14.0) | 65.5 (14.8) | < 0.001 |
Age mean (SDb), years | 34.6 (13.5) | 34.7 (13.7) | 0.299 |
Age group, n (%) | |||
 20–29 | 4302 (50.04) | 17,208 (50.04) |  |
 30–39 | 1939 (22.55) | 7756 (22.55) |  |
 40–49 | 1194 (13.89) | 4776 (13.89) |  |
 50–59 | 617 (7.18) | 2468 (7.18) |  |
 60–69 | 309 (3.59) | 1236 (3.59) |  |
 > 70 | 236 (2.75) | 944 (2.75) | 1.000 |
Sex, n (%) | |||
 Males | 3235 (37.63) | 12,940 (37.63) |  |
 Females | 5362 (62.37) | 21,448 (62.37) | 1.000 |
Charlson Comorbidity Index, n (%) | |||
 0 | 2494 (29.01) | 16,286 (47.36) |  |
 1 | 3963 (46.10) | 13,710 (39.87) |  |
 2 | 1389 (16.16) | 3018 (8.78) |  |
 ≥3 | 751 (8.74) | 1374 (4.00) | < 0.001 |
Co-morbidity, n (%) | |||
 Hyperlipidemia | 1771 (20.60) | 4197 (12.20) | < 0.001 |
 Hypertension | 1513 (17.60) | 3818 (11.10) | < 0.001 |
 Diabetes mellitus | 1049 (12.20) | 2533 (7.37) | < 0.001 |
 Chronic liver disease | 2186 (25.43) | 4947 (14.39) | < 0.001 |
 Chronic kidney disease | 568 (6.61) | 1352 (3.93) | < 0.001 |
 Chronic pulmonary disease | 2887 (33.58) | 8370 (24.34) | < 0.001 |
 Hyperthyroidism | 643 (7.48) | 1424 (4.14) | < 0.001 |
 Hyperparathyroidism | 19 (0.22) | 35 (0.10) | 0.005 |
 Stroke | 262 (3.05) | 530 (1.54) | < 0.001 |
 Depression | 1066 (12.40) | 2274 (6.61) | < 0.001 |
 Alcohol attributed disease | 232 (2.70) | 632 (1.84) | < 0.001 |
 Obesity | 227 (2.64) | 591 (1.72) | < 0.001 |
 Tobacco use disorder | 65 (0.76) | 122 (0.35) | < 0.001 |